1. Gene
  2. WDR3 - WD repeat domain 3 Gene

WDR3 - WD repeat domain 3 Gene

中文名称:WD 重复域 3

种属: Homo sapiens

同用名: DIP2; UTP12

基因 ID: 10885 | 基因类型: protein coding

关于 WDR3

Cytogenetic location: 1p12 Genomic coordinates (GRCh38): 1:117,929,739-117,966,543 (from NCBI)

This gene has 4 transcripts (splice variants), 203 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 13.4), appendix (RPKM 7.9) and 25 other tissues.

功能概要

该基因编码含有 10 个 WD 重复序列的核蛋白。 WD 重复是大约 30 到 40 个氨基酸的结构域,包含几个保守残基,通常在 C 末端包含一个 trp-asp。属于 WD 重复家族的蛋白质参与多种细胞过程,包括细胞周期进程、信号转导、细胞凋亡和基因调控。[RefSeq 提供,2008 年 7 月]

This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins belonging to the WD repeat family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, Apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]

WDR3 基因产物(1)

mRNA Protein Name
NM_006784.3 NP_006775.1 WD repeat-containing protein 3
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ribosomal small subunit biogenesis IDA
IDA: 通过直接分析推断
34516797 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of small-subunit processome IDA
IDA: 通过直接分析推断
34516797 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

WDR3 蛋白结构

WD40

WD40: WD domain, G-beta repeat (58 - 93)

WD40

WD40: WD domain, G-beta repeat (101 - 135)

WD40

WD40: WD domain, G-beta repeat (142 - 177)

WD40

WD40: WD domain, G-beta repeat (183 - 219)

WD40

WD40: WD domain, G-beta repeat (409 - 442)

WD40

WD40: WD domain, G-beta repeat (487 - 524)

WD40

WD40: WD domain, G-beta repeat (551 - 576)

WD40

WD40: WD domain, G-beta repeat (586 - 618)

WD40

WD40: WD domain, G-beta repeat (623 - 661)

WD40

WD40: WD domain, G-beta repeat (666 - 703)

Utp12

Utp12: Dip2/Utp12 Family (804 - 908)

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  • 200
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  • 600
  • 800
  • 943 a.a.
蛋白主名 其他名称

WD repeat-containing protein 3

dJ776P7.2 (WD repeat domain 3)

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta WDR3 VGNC VGNC:78789
Mus musculus WDR3 MGD MGI:2443143
Canis familiaris WDR3 VGNC VGNC:48359
Rattus norvegicus WDR3 RGD RGD:1307480
Bos taurus WDR3 VGNC VGNC:36890
Felis catus WDR3 VGNC VGNC:67024
Others WDR3 NCBI