1. Gene
  2. BTN3A2 - butyrophilin subfamily 3 member A2 Gene

BTN3A2 - butyrophilin subfamily 3 member A2 Gene

中文名称:嗜乳脂蛋白亚家族 3 成员 A2

种属: Homo sapiens

同用名: BTF4; BT3.2; CD277; BTN3.2

基因 ID: 11118 | 基因类型: protein coding

关于 BTN3A2

Cytogenetic location: 6p22.2 Genomic coordinates (GRCh38): 6:26,365,169-26,378,320 (from NCBI)

This gene has 19 transcripts (splice variants), 33 orthologues and 15 paralogues. Ubiquitous expression in spleen (RPKM 42.7), appendix (RPKM 22.0) and 24 other tissues.

功能概要

该基因编码免疫球蛋白超家族的一个成员,该超家族位于主要组织相容性 1 类基因座的近端粒区域,并与 6 号染色体上的其他家族成员聚集在一起。编码的蛋白质可能参与适应性免疫反应。已发现该基因编码不同亚型的可变剪接转录物变体。[RefSeq 提供,2013 年 6 月]

This gene encodes a member of the immunoglobulin superfamily, which resides in the juxta-telomeric region of the major histocompatability class 1 locus and is clustered with the other family members on chromosome 6. The encoded protein may be involved in the adaptive immune response. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]

BTN3A2 基因产物(5)

mRNA Protein Name
NM_001197246.2 NP_001184175.1 butyrophilin subfamily 3 member A2 isoform a precursor
NM_001197247.3 NP_001184176.1 butyrophilin subfamily 3 member A2 isoform a precursor
NM_001197248.3 NP_001184177.1 butyrophilin subfamily 3 member A2 isoform b
NM_001197249.3 NP_001184178.1 butyrophilin subfamily 3 member A2 isoform c
NM_007047.5 NP_008978.2 butyrophilin subfamily 3 member A2 isoform a precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
29339503 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in T cell mediated immunity IMP
IMP: 通过突变表型推断
22767497 GOA
involved in positive regulation of type II interferon production IMP
IMP: 通过突变表型推断
21918970 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
22767497 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

BTN3A2 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (31 - 134)

  • 0
  • 100
  • 200
  • 300
  • 334 a.a.
蛋白主名 其他名称

butyrophilin subfamily 3 member A2

butyrophilin protein

重组 BTN3A2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7684 BTN3A2 Protein, Human (HEK293, His) P78410-1 (Q30-W248) ≥95%
HY-P72346 BTN3A2 Protein, Human (Biotinylated, HEK293, His-Avi) P78410-1 (Q30-W248) ≥95%
HY-P78367 BTN3A2 Protein, Human (HEK293, His-Avi) P78410-1 (Q30-W248) ≥95%