NUDT4 - nudix hydrolase 4 Gene

中文名称：nudix 水解酶 4

种属: Homo sapiens

同用名: DIPP2; NUDT4B; DIPP-2B; HDCMB47P; DIPP2beta; DIPP2alpha

关于 NUDT4

功能概要

该基因编码的蛋白质调节二磷酸肌醇多磷酸盐的转换。这些高能二磷酸肌醇多磷酸盐的周转代表具有重要监管后果的分子转换活动。二磷酸肌醇多磷酸盐的分子转换可能有助于调节细胞内运输。已经描述了几种可变剪接的转录本变体，但尚未确定某些变体的全长性质。异构体 DIPP2alpha 和 DIPP2beta 仅通过 DIPP2beta 彼此区分，由于交替剪接中的内含子边界滑动，DIPP2beta 拥有一个额外的氨基酸。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene regulates the turnover of diphosphoinositol polyphosphates. The turnover of these high-energy diphosphoinositol polyphosphates represents a molecular switching activity with important regulatory consequences. Molecular switching by diphosphoinositol polyphosphates may contribute to regulating intracellular trafficking. Several alternatively spliced transcript variants have been described, but the full-length nature of some variants has not been determined. Isoforms DIPP2alpha and DIPP2beta are distinguishable from each Other solely by DIPP2beta possessing one additional amino acid due to intron boundary skidding in alternate splicing. [provided by RefSeq, Jul 2008]