1. Gene
  2. CTRC - chymotrypsin C Gene

CTRC - chymotrypsin C Gene

中文名称:糜蛋白酶 C

种属: Homo sapiens

同用名: CLCR; ELA4

基因 ID: 11330 | 基因类型: protein coding

关于 CTRC

Cytogenetic location: 1p36.21 Genomic coordinates (GRCh38): 1:15,438,443-15,449,242 (from NCBI)

This gene has 4 transcripts (splice variants), 102 orthologues, 2 paralogues and is associated with 4 phenotypes. Restricted expression toward pancreas (RPKM 2413.6).

功能概要

该基因编码肽酶 S1 家族的一个成员。编码的蛋白质是一种血清钙降低因子,具有胰凝乳蛋白酶样蛋白酶活性。已观察到可变剪接的转录本变体,但尚未确定其全长性质。[RefSeq 提供,2008 年 7 月]

This gene encodes a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like Protease activity. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

CTRC 基因产物(1)

mRNA Protein Name
NM_007272.3 NP_009203.2 chymotrypsin-C preproprotein
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables peptidase activity IDA
IDA: 通过直接分析推断
8635596 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within intracellular calcium ion homeostasis IDA
IDA: 通过直接分析推断
8635596 GOA
acts upstream of or within proteolysis IDA
IDA: 通过直接分析推断
8635596 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CTRC 蛋白结构

Trypsin

Trypsin: Trypsin (30 - 262)

  • 0
  • 100
  • 200
  • 268 a.a.
蛋白主名 其他名称

chymotrypsin-C

caldecrin

重组 CTRC 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70098 CTRC Protein, Human (HEK293, His) Q99895 (C17-L268) ≥95%

关联疾病

疾病名称 别名
Pancreatitis, Hereditary

Hereditary Pancreatitis

Chronic Pancreatitis

Hereditary Chronic Pancreatitis

Hp

Pancreatitis, Chronic, Susceptibility To

PCTT

Hpc

Pancreatitis, Chronic

Pancreatitis, Chronic, Protection Against

Autosomal Dominant Hereditary Pancreatitis

Familial Pancreatitis

Cp

Pancreatitis Hereditary

Prss1-Related Hereditary Pancreatitis
Tropical Calcific Pancreatitis

Tropical Pancreatitis

TCP

Fibrocalculous Pancreatic Diabetes

Tropical Calcific Chronic Pancreatitis

Fibrocalculous Pancreatic Diabetes, Susceptibility To

Tcp - [Tropical Chronic Pancreatitis]

Pancreatitis

Mumps Pancreatitis

Acute Pancreatitis

Pancreatitis

Pancreatitis, Acute Necrotizing

Pancreatitis Nos

Acute Pancreas Inflammation

Pancreas, Annular

Annular Pancreas

Pancreas Annulare

Congenital Annular Pancreas

Alcoholic Pancreatitis

Pancreatitis, Alcoholic

Pancreatitis Alcoholic

Bile Duct Cysts

Choledochal Cyst

Choledochal Cysts

Choledochocele

Biliary Cyst

Congenital Choledochal Cyst

Bile Duct Cyst

Congenital Cystic Dilatation Of The Biliary Tract

Congenital Bile Duct Dilatation

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus CTRC VGNC VGNC:27811
Felis catus CTRC VGNC VGNC:61263
Rattus norvegicus CTRC RGD RGD:1308379
Mus musculus CTRC MGD MGI:1923951
Others CTRC NCBI