2. Gene
  3. Acsl4 - acyl-CoA synthetase long-chain family member 4 Gene

Acsl4 - acyl-CoA synthetase long-chain family member 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Acs4; Facl4

基因 ID: 113976 | 基因类型: protein coding

关于 Acsl4

功能概要

Enables arachidonate-CoA Ligase activity. Involved in several processes, including dendritic spine development; long-chain fatty-acyl-CoA biosynthetic process; and positive regulation of Insulin secretion. Located in mitochondrial membrane; neuronal cell body; and peroxisome. Colocalizes with endoplasmic reticulum. Human ortholog(s) of this gene implicated in intellectual disability and non-syndromic X-linked intellectual disability 63. Orthologous to human ACSL4 (acyl-CoA synthetase long chain family member 4). [provided by Alliance of Genome Resources, Apr 2022]

Acsl4 基因产物(1)

mRNA Protein Name
NM_053623.1 NP_446075.1 long-chain-fatty-acid--CoA ligase 4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables arachidonate-CoA ligase activity IDA
IDA: 通过直接分析推断
28209804 RGD
enables long-chain fatty acid-CoA ligase activity IDA
IDA: 通过直接分析推断
9096315 RGD
enables long-chain fatty acid-CoA ligase activity IMP
IMP: 通过突变表型推断
23766516 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in dendritic spine development IMP
IMP: 通过突变表型推断
19166906 RGD
involved in fatty acid metabolic process IDA
IDA: 通过直接分析推断
9096315 RGD
involved in fatty acid transport IGI
IGI: 通过遗传相互作用推断
16466685 RGD
involved in long-chain fatty acid metabolic process IDA
IDA: 通过直接分析推断
28209804 RGD
involved in long-chain fatty-acyl-CoA biosynthetic process IGI
IGI: 通过遗传相互作用推断
16466685 RGD
involved in positive regulation of insulin secretion IMP
IMP: 通过突变表型推断
23766516 RGD
involved in response to interleukin-15 IEP
IEP: 通过表达模式推断
18239634 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
16772660 RGD
involved in triglyceride biosynthetic process IGI
IGI: 通过遗传相互作用推断
16466685 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial membrane IDA
IDA: 通过直接分析推断
12147264 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
19166906 RGD
located in peroxisome IDA
IDA: 通过直接分析推断
12147264 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

long-chain-fatty-acid--CoA ligase 4

LACS 4

arachidonate--CoA ligase

fatty acid-Coenzyme A ligase, long chain 4

long-chain acyl-CoA synthetase 4

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-139180 PRGL493 Inhibitor 99.64% 否
HY-RS16244 Acsl4 Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS00202 ACSL4 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-155851 Lepadin E / 否
HY-155852 Lepadin H Inducer / 否
HY-115701 1-Stearoyl-2-15(S)-Hpete-Sn-Glycero-3-Pe / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Acsl4 NCBI NCBI:2182
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