1. Gene
  2. Chrna1 - cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) Gene

Chrna1 - cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) Gene

种属: Mus musculus

同用名: Acra; Achr-1

基因 ID: 11435 | 基因类型: protein coding

关于 Chrna1

功能概要

This gene encodes an alpha subunit of the muscle-derived nicotinic acetylcholine receptor, a pentameric neurotransmitter receptor and member of the ligand-gated ion channel superfamily. The alpha subunit plays a role in substrate binding and channel gating. [provided by RefSeq, Nov 2012]

Chrna1 基因产物(1)

mRNA Protein Name
NM_007389.5 NP_031415.2 acetylcholine receptor subunit alpha precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
contributes to acetylcholine binding IGI
IGI: 通过遗传相互作用推断
8910344 MGI
contributes to acetylcholine receptor activity IDA
IDA: 通过直接分析推断
8872460 MGI
contributes to acetylcholine-gated monoatomic cation-selective channel activity IGI
IGI: 通过遗传相互作用推断
2383398 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
21187406 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within regulation of membrane potential IGI
IGI: 通过遗传相互作用推断
2383398 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of acetylcholine-gated channel complex IPI
IPI: 通过物理相互作用推断
8910344 MGI
located in cell surface IDA
IDA: 通过直接分析推断
21187406 MGI
located in membrane IDA
IDA: 通过直接分析推断
20053883 MGI
is active in neuromuscular junction IDA
IDA: 通过直接分析推断
4781450 MGI
located in neuromuscular junction IDA
IDA: 通过直接分析推断
16203963 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
12388596 MGI
is active in postsynaptic specialization membrane IDA
IDA: 通过直接分析推断
4781450 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

acetylcholine receptor subunit alpha

重组 Chrna1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72141 CHRNA1 Protein, Mouse (His) P04756 (S21-L230) ≥95%
HY-P72142 CHRNA1 Protein, Mouse (His-SUMO) P04756 (S21-L230) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Chrna1 NCBI NCBI:1134