2. Gene
  3. GALNT13 - polypeptide N-acetylgalactosaminyltransferase 13 Gene

GALNT13 - polypeptide N-acetylgalactosaminyltransferase 13 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：多肽 N-乙酰半乳糖氨基转移酶 13

种属: Homo sapiens

同用名: GalNAc-T13

基因 ID: 114805 | 基因类型: protein coding

关于 GALNT13

Cytogenetic location: 2q23.3-q24.1 Genomic coordinates (GRCh38): 2:153,732,769-154,454,177 (from NCBI)

This gene has 10 transcripts (splice variants), 242 orthologues and 19 paralogues. Biased expression in brain (RPKM 11.3), adrenal (RPKM 2.3) and 5 other tissues.

功能概要

GALNT13 蛋白是 UDP-N-乙酰基-α-D-半乳糖胺：多肽 N-乙酰半乳糖胺基转移酶 (GalNAcT; EC 2.4.1.41) 家族的成员，它通过 N-乙酰半乳糖胺 (GalNAc) 与丝氨酸或苏氨酸残基的α连接的初始转移。[OMIM 提供，2004 年 4 月]

The GALNT13 protein is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAcT; EC 2.4.1.41) family, which initiate O-linked glycosylation of mucins (see MUC3A, MIM 158371) by the initial transfer of N-acetylgalactosamine (GalNAc) with an alpha-linkage to a serine or threonine residue.[supplied by OMIM, Apr 2004]

GALNT13 基因产物(11)

mRNA Protein Name
NM_001301627.2 NP_001288556.1 polypeptide N-acetylgalactosaminyltransferase 13 isoform 2
NM_001376392.1 NP_001363321.1 polypeptide N-acetylgalactosaminyltransferase 13 isoform 1
NM_001376394.1 NP_001363323.1 polypeptide N-acetylgalactosaminyltransferase 13 isoform 1
NM_001376398.1 NP_001363327.1 polypeptide N-acetylgalactosaminyltransferase 13 isoform 1
NM_001376400.1 NP_001363329.1 polypeptide N-acetylgalactosaminyltransferase 13 isoform 1
NM_001376401.1 NP_001363330.1 polypeptide N-acetylgalactosaminyltransferase 13 isoform 1
NM_001376402.1 NP_001363331.1 polypeptide N-acetylgalactosaminyltransferase 13 isoform 1
NM_001376403.1 NP_001363332.1 polypeptide N-acetylgalactosaminyltransferase 13 isoform 3
NM_001376404.1 NP_001363333.1 polypeptide N-acetylgalactosaminyltransferase 13 isoform 3
NM_001376405.1 NP_001363334.1 polypeptide N-acetylgalactosaminyltransferase 13 isoform 4
NM_052917.4 NP_443149.2 polypeptide N-acetylgalactosaminyltransferase 13 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables polypeptide N-acetylgalactosaminyltransferase activity IDA
IDA: 通过直接分析推断
22186971 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in protein O-linked glycosylation via serine IDA
IDA: 通过直接分析推断
22186971 GOA
involved in protein O-linked glycosylation via threonine IDA
IDA: 通过直接分析推断
22186971 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

GALNT13 蛋白结构

Glycos_transf_2

Glycos_transf_2: Glycosyl transferase family 2 (118 - 301)

Ricin_B_lectin

Ricin_B_lectin: Ricin-type beta-trefoil lectin domain (431 - 547)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 556 a.a.
蛋白主名 其他名称

polypeptide N-acetylgalactosaminyltransferase 13

GalNAc transferase 13

关联疾病

疾病名称 别名
Sphenoorbital Meningioma
Tricuspid Valve Insufficiency

Tricuspid Regurgitation

Tricuspid Valve Regurgitation

Tricuspid Incompetence

Tr - [Tricuspid Regurgitation]

Tricuspid Valve Incompetency

Tricuspid Valve Annular Incompetency
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-E70294 N-Acetylgalactosaminyltransferase 13 / 否
HY-RS05251 GALNT13 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus GALNT13 RGD RGD:735044
Canis familiaris GALNT13 VGNC VGNC:41088
Mus musculus GALNT13 MGD MGI:2139447
Bos taurus GALNT13 VGNC VGNC:29226
Macaca mulatta GALNT13 VGNC VGNC:104531
Felis catus GALNT13 VGNC VGNC:62445
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z