2. Gene
  3. Adam15 - a disintegrin and metallopeptidase domain 15 (metargidin) Gene

Adam15 - a disintegrin and metallopeptidase domain 15 (metargidin) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: AD56; MDC15

基因 ID: 11490 | 基因类型: protein coding

关于 Adam15

功能概要

This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. This gene is prominently expressed in vascular cells, the endocardium, hypertrophic cells in developing bone, and specific areas of hippocampus and cerebellum. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. Mice lacking the encoded protein have increased bone mass resulting from osteoblast proliferation, and exhibit reduced neovascularization in a mouse model for retinopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing. [provided by RefSeq, May 2016]

Adam15 基因产物(13)

mRNA Protein Name
NM_001037722.4 NP_001032811.2 disintegrin and metalloproteinase domain-containing protein 15 isoform a preproprotein
NM_001409479.1 NP_001396408.1 disintegrin and metalloproteinase domain-containing protein 15 isoform c preproprotein
NM_001409480.1 NP_001396409.1 disintegrin and metalloproteinase domain-containing protein 15 isoform d preproprotein
NM_001409481.1 NP_001396410.1 disintegrin and metalloproteinase domain-containing protein 15 isoform e preproprotein
NM_001409482.1 NP_001396411.1 disintegrin and metalloproteinase domain-containing protein 15 isoform f precursor
NM_001409483.1 NP_001396412.1 disintegrin and metalloproteinase domain-containing protein 15 isoform g precursor
NM_001409484.1 NP_001396413.1 disintegrin and metalloproteinase domain-containing protein 15 isoform h precursor
NM_001409485.1 NP_001396414.1 disintegrin and metalloproteinase domain-containing protein 15 isoform i
NM_001409486.1 NP_001396415.1 disintegrin and metalloproteinase domain-containing protein 15 isoform j precursor
NM_001409487.1 NP_001396416.1 disintegrin and metalloproteinase domain-containing protein 15 isoform k precursor
NM_001409488.1 NP_001396417.1 disintegrin and metalloproteinase domain-containing protein 15 isoform m
NM_001409489.1 NP_001396418.1 disintegrin and metalloproteinase domain-containing protein 15 isoform l
NM_009614.4 NP_033744.1 disintegrin and metalloproteinase domain-containing protein 15 isoform b precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10531379 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cardiac epithelial to mesenchymal transition IMP
IMP: 通过突变表型推断
19156209 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

disintegrin and metalloproteinase domain-containing protein 15

a disintegrin and metalloprotease domain 15 (metargidin)

metalloprotease RGD disintegrin protein

metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15

重组 Adam15 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75564 ADAM15 Protein, Mouse (HEK293, His) O88839 (R18-T697) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00270 ADAM15 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adam15 NCBI NCBI:8751
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