Adh5 - alcohol dehydrogenase 5 (class III), chi polypeptide Gene

中文名称：乙醇脱氢酶 5 ( II I 类) ，χ 多肽

种属: Mus musculus

同用名: Adh3; Adh-5; GSNOR

关于 Adh5

功能概要

该基因编码的蛋白可启动 S-(羟甲基) 谷胱甘肽脱氢酶活性；乙醇脱氢酶 (NAD+) 活性；和相同的蛋白质结合活性。作用于多个过程的上游或内部，包括甲醛分解代谢过程；肽基-半胱氨酸 S-亚硝基化；和对脂多糖的反应。位于线粒体中。以多种结构表达，包括消化系统；中枢神经系统;泌尿生殖系统；外皮系统；和呼吸系统。该基因的人类直系同源物与 AMED 综合征和哮喘有关。与人 ADH5（酒精脱氢酶 5（III 类），chi 多肽）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables S-(hydroxymethyl)glutathione dehydrogenase activity; alcohol dehydrogenase (NAD+) activity; and identical protein binding activity. Acts upstream of or within several processes, including formaldehyde catabolic process; peptidyl-cysteine S-nitrosylation; and response to lipopolysaccharide. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and respiratory system. Human ortholog(s) of this gene implicated in AMED syndrome and asthma. Orthologous to human ADH5 (alcohol dehydrogenase 5 (class III), chi polypeptide). [provided by Alliance of Genome Resources, Apr 2022]