1. Gene
  2. WDFY2 - WD repeat and FYVE domain containing 2 Gene

WDFY2 - WD repeat and FYVE domain containing 2 Gene

中文名称:含 WD 重复和 FYVE 结构域 2

种属: Homo sapiens

同用名: PROF; WDF2; ZFYVE22

基因 ID: 115825 | 基因类型: protein coding

关于 WDFY2

Cytogenetic location: 13q14.3 Genomic coordinates (GRCh38): 13:51,584,462-51,767,709 (from NCBI)

This gene has 3 transcripts (splice variants), 220 orthologues and 10 paralogues. Ubiquitous expression in skin (RPKM 5.8), bone marrow (RPKM 4.0) and 25 other tissues.

功能概要

该基因编码的蛋白质包含两个 WD 结构域和一个 FYVE 锌指区域。该基因的功能未知。可能存在该基因的选择性剪接转录变体。[RefSeq 提供,2008 年 7 月]

This gene encodes a protein that contains two WD domains and an FYVE zinc finger region. The function of this gene is unknown. An alternatively spliced transcript variant of this gene may exist. [provided by RefSeq, Jul 2008]

WDFY2 基因产物(1)

mRNA Protein Name
NM_052950.4 NP_443182.1 WD repeat and FYVE domain-containing protein 2

WDFY2 蛋白结构

WD40

WD40: WD domain, G-beta repeat (190 - 227)

WD40

WD40: WD domain, G-beta repeat (237 - 270)

FYVE

FYVE: FYVE zinc finger (284 - 351)

WD40

WD40: WD domain, G-beta repeat (358 - 394)

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蛋白主名 其他名称

WD repeat and FYVE domain-containing protein 2

WD40 and FYVE domain containing 2

WDFY2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
WDFY2 Q96P53 RPRM Homo sapiens Q9NS64
Y2H Array
32296183
种属内
WDFY2 Q96P53 RPRM Homo sapiens Q9NS64
Y2H Prey Pooling
32296183
种属内
WDFY2 Q96P53 RPRM Homo sapiens Q9NS64
Validated Y2H
32296183
种属内
WDFY2 Q96P53 YIF1A Homo sapiens O95070
Y2H Array
32296183
种属内
WDFY2 Q96P53 YIF1A Homo sapiens O95070
Y2H Prey Pooling
32296183
种属内
WDFY2 Q96P53 NUDC Homo sapiens Q9Y266
Anti Tag CoIP
33961781
种属内
WDFY2 Q96P53 NUDC Homo sapiens Q9Y266
Lumier
25036637
种属内
WDFY2 Q96P53 ARL6IP1 Homo sapiens Q15041
Y2H Array
32296183
种属内
WDFY2 Q96P53 ARL6IP1 Homo sapiens Q15041
Y2H Prey Pooling
32296183
种属内
WDFY2 Q96P53 SYP Homo sapiens P08247
Y2H Prey Pooling
32296183
种属内
WDFY2 Q96P53 SYP Homo sapiens P08247
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Hyperglobulinemic Purpura

Purpura, Hyperglobulinemic

Laryngeal Tuberculosis

Tuberculosis, Laryngeal

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus WDFY2 RGD RGD:1307337
Felis catus WDFY2 VGNC VGNC:67010
Canis familiaris WDFY2 VGNC VGNC:54388
Mus musculus WDFY2 MGD MGI:2442811
Bos taurus WDFY2 VGNC VGNC:53847
Macaca mulatta WDFY2 VGNC VGNC:97842