2. Gene
  3. OSR2 - odd-skipped related transciption factor 2 Gene

OSR2 - odd-skipped related transciption factor 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：奇数跳跃相关转录因子 2

种属: Homo sapiens

基因 ID: 116039 | 基因类型: protein coding

关于 OSR2

Cytogenetic location: 8q22.2 Genomic coordinates (GRCh38): 8:98,944,442-98,952,100 (from NCBI)

This gene has 10 transcripts (splice variants), 197 orthologues and 1 paralogue. Biased expression in endometrium (RPKM 68.5), ovary (RPKM 33.5) and 8 other tissues.

功能概要

OSR2 是果蝇奇数跳跃转录因子家族的哺乳动物同系物 (Lan 等人，2004 [PubMed 15175245]) 。[OMIM 提供，2008 年 3 月]

OSR2 is a mammalian homolog of the Drosophila odd-skipped family of transcription factors (Lan et al., 2004 [PubMed 15175245]).[supplied by OMIM, Mar 2008]

OSR2 基因产物(4)

mRNA Protein Name
NM_001142462.3 NP_001135934.1 protein odd-skipped-related 2 isoform a
NM_001286841.2 NP_001273770.1 protein odd-skipped-related 2 isoform c
NM_001394683.1 NP_001381612.1 protein odd-skipped-related 2 isoform d
NM_053001.4 NP_443727.2 protein odd-skipped-related 2 isoform b
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: 通过直接分析推断
28473536 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

OSR2 蛋白结构

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (186 - 210)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (214 - 237)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (256 - 278)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (284 - 306)

  • 0
  • 100
  • 200
  • 312 a.a.
蛋白主名 其他名称

protein odd-skipped-related 2

odd-skipped related 2

OSR2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
OSR2 Q8N2R0 PSMA3 Homo sapiens P25788
Y2H Array
25416956
种属内
OSR2 Q8N2R0 PSMA3 Homo sapiens P25788
Y2H Prey Pooling
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Cleft Soft Palate

Cleft Velum

Cleft Velum Palatinum

Soft Cleft Palate

Soft Palate Perforation
Blepharophimosis, Ptosis, And Epicanthus Inversus

Blepharophimosis, Ptosis, And Epicanthus Inversus Syndrome

BPES

Blepharophimosis Syndrome

Blepharophimosis, Epicanthus Inversus, And Ptosis, Type 1

Blepharophimosis, Ptosis, Epicanthus Inversus Syndrome

Bpes With Duane Retraction Syndrome

Blepharophimosis, Ptosis, And Epicanthus Inversus Syndrome Type 2

Blepharophimosis, Ptosis, And Epicanthus Inversus Syndrome Type 1

Blepharophimosis, Epicanthus Inversus, And Ptosis, Type 2

Blepharophimosis-Ptosis-Epicanthus Inversus Syndrome

Blepharophimosis-Ptosis-Epicanthus Inversus Syndrome Type 2

Bpes Type 2

Blepharophimosis-Ptosis-Epicanthus Inversus Syndrome Without Premature Ovarian Failure

Blepharophimosis-Ptosis-Epicanthus Inversus Syndrome Plus

3q23 Microdeletion Syndrome

Bpes Plus

Blepharophimosis-Ptosis-Epicanthus Inversus Syndrome Type 1

Bpes Type 1

Blepharophimosis-Ptosis-Epicanthus Inversus Syndrome With Premature Ovarian Failure

Blepharophimosis, Ptosis, Epicanthus Inversus

Autosomal Dominant Bpes Type I

Autosomal Recessive Bpes Type I

Bpes Type I

Bpes Type Ii

Bpes Without Ovarian Failure

Bpes With Ovarian Failure

Blepharophimosis Syndrome Type 1

Blepharophimosis Syndrome Type 2
Cleft Palate, Isolated

Cleft Palate

Isolated Cleft Palate

CPI

Cp

Palatoschisis

Cleft Palate Isolated

Uranostaphyloschisis

Congenital Fissure Of Palate

Cleft Of Secondary Palate
Peptic Ulcer Perforation

Perforated Peptic Ulcer

Acute Peptic Ulcer With Perforation

Peptic Ulcer With Perforation
Cleft Palate With Or Without Ankyloglossia, X-Linked

Cleft Palate With Ankyloglossia

CPX

X-Linked Cleft Palate And Ankyloglossia

X-Linked Cleft Palate With Or Without Ankyloglossia

X-Linked Cleft Palate

X-Linked Cleft Palate With Ankyloglossia

Cleft Palate, With/Without Ankyloglossia, X-Linked
Orofacial Cleft

Cleft, Orofacial
Tooth Agenesis

Oligodontia

Hypodontia

Selective Tooth Agenesis

Tooth Agenesis, Selective

Familial Tooth Agenesis

Anodontia

Congenital Absence Of One Tooth
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09853 OSR2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta OSR2 VGNC VGNC:84097
Rattus norvegicus OSR2 RGD RGD:1305812
Canis familiaris OSR2 VGNC VGNC:44169
Bos taurus OSR2 VGNC VGNC:32477
Felis catus OSR2 VGNC VGNC:63990
Mus musculus OSR2 MGD MGI:1930813
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