2. Gene
  3. Aif1 - allograft inflammatory factor 1 Gene

Aif1 - allograft inflammatory factor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: G1; Iba1; AIF-1; D17H6S50E

基因 ID: 11629 | 基因类型: protein coding

关于 Aif1

功能概要

Enables actin filament binding activity and calcium ion binding activity. Involved in several processes, including Rac protein signal transduction; actin filament organization; and ruffle assembly. Acts upstream of or within actin filament bundle assembly. Located in several cellular components, including actin filament; phagocytic cup; and ruffle membrane. Is expressed in adrenal cortex; central nervous system; embryo mesenchyme; and retina. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human AIF1 (allograft inflammatory factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Aif1 基因产物(5)

mRNA Protein Name
NM_001361501.2 NP_001348430.1 allograft inflammatory factor 1 isoform a
NM_001361502.2 NP_001348431.1 allograft inflammatory factor 1 isoform b
NM_001409899.1 NP_001396828.1 allograft inflammatory factor 1 isoform a
NM_001409902.1 NP_001396831.1 allograft inflammatory factor 1 isoform a
NM_019467.4 NP_062340.1 allograft inflammatory factor 1 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin filament binding IMP
IMP: 通过突变表型推断
11500035 MGI
enables calcium ion binding IDA
IDA: 通过直接分析推断
17011575 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
14756805 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Rac protein signal transduction IMP
IMP: 通过突变表型推断
10934045 MGI
involved in actin crosslink formation IMP
IMP: 通过突变表型推断
11500035 MGI
acts upstream of or within actin filament bundle assembly IDA
IDA: 通过直接分析推断
14756805 MGI
involved in parallel actin filament bundle assembly IDA
IDA: 通过直接分析推断
11500035 MGI
involved in phagocytosis, engulfment IMP
IMP: 通过突变表型推断
10934045 MGI
involved in ruffle assembly IMP
IMP: 通过突变表型推断
10934045 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin filament IDA
IDA: 通过直接分析推断
14756805 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
10934045 MGI
located in glial cell projection IDA
IDA: 通过直接分析推断
14756805 MGI
located in lamellipodium IDA
IDA: 通过直接分析推断
10934045 MGI
located in nucleus IDA
IDA: 通过直接分析推断
10934045 MGI
located in phagocytic cup IDA
IDA: 通过直接分析推断
10934045 MGI
located in ruffle IDA
IDA: 通过直接分析推断
14756805 MGI
located in ruffle membrane IDA
IDA: 通过直接分析推断
10934045 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

allograft inflammatory factor 1

ionized calcium binding adapter molecule 1

testis specific

重组 Aif1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72075 AIF1 Protein, Mouse (His) O70200 (S2-P147) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-113915 Kuguaglycoside C Inducer / 否
HY-RS00490 AIF1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS00491 AIF1L Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Aif1 NCBI NCBI:199
Macaca fascicularis Aif1 NCBI NCBI:102132908
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z