IL22RA2 - interleukin 22 receptor subunit alpha 2 Gene

中文名称：白细胞介素 22 受体亚基 α 2

种属: Homo sapiens

同用名: CRF2X; CRF2-10; CRF2-S1; IL-22BP; IL-22RA2; ZCYTOR16; IL-22R-alpha-2

关于 IL22RA2

功能概要

该基因编码 II 类细胞因子受体家族的成员。编码的可溶性蛋白通过阻断白细胞介素 22 与其细胞表面受体的相互作用，特异性结合并抑制白细胞介素 22 的活性。编码的蛋白质可能在炎症反应的调节中起重要作用，并且与结肠肿瘤发生的调节有关。可变剪接导致编码不同异构体的多个转录变体。[RefSeq 提供，2013 年 7 月]

This gene encodes a member of the class II cytokine receptor family. The encoded soluble protein specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor. The encoded protein may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]