2. Gene
  3. Fcgr2a - Fc gamma receptor 2A Gene

Fcgr2a - Fc gamma receptor 2A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Fcgr3; Fcgr3a

基因 ID: 116591 | 基因类型: protein coding

关于 Fcgr2a

功能概要

Enables immunoglobulin receptor binding activity. Involved in several processes, including regulation of Fc-gamma Receptor signaling pathway involved in phagocytosis; regulation of antibody-dependent cellular cytotoxicity; and regulation of tumor necrosis factor production. Located in cell surface. Used to study crescentic glomerulonephritis. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dengue disease (multiple); hematologic Cancer (multiple); leukopenia (multiple); and malaria (multiple). Orthologous to human FCGR2A (Fc fragment of IgG receptor IIa). [provided by Alliance of Genome Resources, Apr 2022]

Fcgr2a 基因产物(1)

mRNA Protein Name
NM_053843.3 NP_446295.2 low affinity immunoglobulin gamma Fc region receptor III
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables immunoglobulin receptor binding IDA
IDA: 通过直接分析推断
22184119 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in nerve development IEP
IEP: 通过表达模式推断
1533683 RGD
involved in regulation of Fc receptor mediated stimulatory signaling pathway IMP
IMP: 通过突变表型推断
16482158 RGD
involved in regulation of antibody-dependent cellular cytotoxicity IMP
IMP: 通过突变表型推断
16482158 RGD
involved in regulation of phagocytosis IMP
IMP: 通过突变表型推断
16482158 RGD
involved in regulation of tumor necrosis factor production IMP
IMP: 通过突变表型推断
22184119 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
22184119 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

low affinity immunoglobulin gamma Fc region receptor III

Fc fragment of IgG low affinity IIa receptor for (CD32)

Fc fragment of IgG receptor IIa

Fc fragment of IgG, low affinity IIa, receptor (CD32)

Fc gamma receptor IIa

Fc receptor, IgG, low affinity III

fc-gamma RIII

fcRIII

igG Fc receptor III

重组 Fcgr2a 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76233 Fc gamma RIIA/CD32a Protein, Rat (HEK293, Fc) A0A8L2Q236/NP_446295 (D32-L216) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04828 FCGR2A Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fcgr2a NCBI NCBI:2212
Macaca fascicularis Fcgr2a NCBI NCBI:102143568
Macaca mulatta Fcgr2a NCBI NCBI:719996
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