2. Gene
  3. Fabp4 - fatty acid binding protein 4, adipocyte Gene

Fabp4 - fatty acid binding protein 4, adipocyte Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ap2; P15; ALBP; Lbpl; AFABP; 422/aP2; ALBP/Ap2

基因 ID: 11770 | 基因类型: protein coding

关于 Fabp4

功能概要

Enables hormone receptor binding activity; long-chain fatty acid binding activity; and long-chain fatty acid transporter activity. Involved in long-chain fatty acid transport and positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including brown fat cell differentiation; cellular response to lithium ion; and negative regulation of nitrogen compound metabolic process. Located in cytoplasm and nucleus. Is expressed in several structures, including adipose tissue; central nervous system; genitourinary system; gut; and heart. Orthologous to human FABP4 (fatty acid binding protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Fabp4 基因产物(3)

mRNA Protein Name
NM_001409513.1 NP_001396442.1 fatty acid-binding protein, adipocyte isoform 2
NM_001409514.1 NP_001396443.1 fatty acid-binding protein, adipocyte isoform 3
NM_024406.4 NP_077717.1 fatty acid-binding protein, adipocyte isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables hormone receptor binding IPI
IPI: 通过物理相互作用推断
12077340 MGI
enables long-chain fatty acid binding IDA
IDA: 通过直接分析推断
12077340 MGI
enables long-chain fatty acid transmembrane transporter activity IDA
IDA: 通过直接分析推断
12077340 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within brown fat cell differentiation IDA
IDA: 通过直接分析推断
18492766 MGI
acts upstream of or within cellular response to lithium ion IDA
IDA: 通过直接分析推断
15673614 MGI
acts upstream of or within cellular response to tumor necrosis factor IDA
IDA: 通过直接分析推断
1618860 MGI
acts upstream of or within cholesterol homeostasis IMP
IMP: 通过突变表型推断
15684432 MGI
acts upstream of or within cytokine production IMP
IMP: 通过突变表型推断
15684432 MGI
involved in long-chain fatty acid transport IDA
IDA: 通过直接分析推断
12077340 MGI
acts upstream of or within negative regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
15684432 MGI
acts upstream of or within negative regulation of protein kinase activity IMP
IMP: 通过突变表型推断
15684432 MGI
involved in positive regulation of cold-induced thermogenesis IGI
IGI: 通过遗传相互作用推断
24603714 MGI
acts upstream of or within positive regulation of inflammatory response IMP
IMP: 通过突变表型推断
15684432 MGI
acts upstream of or within response to bacterium IEP
IEP: 通过表达模式推断
23012479 MGI
acts upstream of or within white fat cell differentiation IDA
IDA: 通过直接分析推断
18492766 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
17516629 MGI
located in nucleus IDA
IDA: 通过直接分析推断
17516629 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

fatty acid-binding protein, adipocyte

3T3-L1 lipid-binding protein

P2 adipocyte protein

adipocyte lipid-binding protein

adipocyte protein aP2

adipocyte-type fatty acid-binding protein

fatty acid-binding protein 4

myelin P2 protein homolog

protein 422

重组 Fabp4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75215 FABP4 Protein, Mouse (His) NP_077717.1 (C2-A132) ≥95%
HY-P75217 FABP4 Protein, Mouse (HEK293, His) Q542H7 (M1-A132) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (11)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-101903 BMS-309403 Inhibitor 99.93% 否
HY-101903A BMS-309403 sodium Inhibitor 99.94% 否
HY-148665 FABP-IN-2 Inhibitor 99.78% 否
HY-149953 FABP4-IN-2 Inhibitor / 否
HY-161702 RO6806051 Inhibitor 99.84% 否
HY-161892 FABP4-IN-4 Inhibitor / 否
HY-P10873 ST-CY14 / 否
HY-RS04660 FABP4 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-160456 FABP4/5-IN-4 Inhibitor / 否
HY-160457 FABP4/5-IN-5 Inhibitor / 否
HY-163032 FABP4-IN-3 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fabp4 NCBI NCBI:2167
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