2. Gene
  3. Arg2 - arginase type II Gene

Arg2 - arginase type II Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: AII

基因 ID: 11847 | 基因类型: protein coding

关于 Arg2

功能概要

Predicted to enable Arginase activity; manganese ion binding activity; and nitric-oxide synthase binding activity. Involved in several processes, including negative regulation of CD4-positive, alpha-beta T cell proliferation; negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process; and negative regulation of cytokine production. Acts upstream of or within striated muscle contraction and ureteric bud development. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in asthma. Orthologous to human ARG2 (Arginase 2). [provided by Alliance of Genome Resources, Apr 2022]

Arg2 基因产物(1)

mRNA Protein Name
NM_009705.3 NP_033835.1 arginase-2, mitochondrial precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of CD4-positive, alpha-beta T cell proliferation IMP
IMP: 通过突变表型推断
25009204 MGI
involved in negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process IMP
IMP: 通过突变表型推断
27745970 MGI
involved in negative regulation of chemokine (C-C motif) ligand 4 production IMP
IMP: 通过突变表型推断
27074721 MGI
involved in negative regulation of chemokine (C-C motif) ligand 5 production IMP
IMP: 通过突变表型推断
27074721 MGI
involved in negative regulation of defense response to bacterium IMP
IMP: 通过突变表型推断
27074721 MGI
involved in negative regulation of interleukin-13 production IMP
IMP: 通过突变表型推断
27214549 MGI
involved in negative regulation of interleukin-17 production IMP
IMP: 通过突变表型推断
27214549 MGI
involved in negative regulation of macrophage inflammatory protein 1 alpha production IMP
IMP: 通过突变表型推断
27074721 MGI
involved in negative regulation of tumor necrosis factor production IMP
IMP: 通过突变表型推断
27074721 MGI
involved in negative regulation of type 2 immune response IMP
IMP: 通过突变表型推断
27214549 MGI
involved in regulation of interleukin-1 beta production IMP
IMP: 通过突变表型推断
27074721 MGI
involved in regulation of reactive oxygen species biosynthetic process IMP
IMP: 通过突变表型推断
27214549 MGI
acts upstream of or within striated muscle contraction IMP
IMP: 通过突变表型推断
16537391 MGI
involved in ureteric bud development IEP
IEP: 通过表达模式推断
16545622 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
25009204 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

arginase-2, mitochondrial

arginase II

kidney-type arginase

non-hepatic arginase

type II arginase

重组 Arg2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72090 Arginase-2/ARG2 Protein, Mouse (His-SUMO) O08691 (V23-I354) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-112885B nor-NOHA monoacetate Inhibitor 99.96% 否
HY-112885C nor-NOHA dihydrochloride 98.85% 否
HY-P4750 Acetyl-(D-Arg2)-GRF (1-29) amide (human) Antagonist 99.67% 否
HY-112885A nor-NOHA acetate ≥99.0% 否
HY-RS00908 ARG2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-112885 nor-NOHA / 否
HY-P10555 (D-Arg2, Sar 4)-Dermorphin (1-4) Agonist / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Arg2 NCBI NCBI:384
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