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  2. Bmx - BMX non-receptor tyrosine kinase Gene

Bmx - BMX non-receptor tyrosine kinase Gene

中文名称:BMX 非受体酪氨酸激酶

种属: Mus musculus

同用名: Etk; Tyro8; Etk/Bmx

基因 ID: 12169 | 基因类型: protein coding

关于 Bmx

Chromosome X: 162,975,838-163,041,189 reverse strand.GRCm39:CM001013.3

This gene has 2 transcripts (splice variants), 137 orthologues, 32 paralogues and is associated with 2 phenotypes. Broad expression in bladder adult (RPKM 1.1), lung adult (RPKM .9) and 22 other tissues.

功能概要

预计该基因编码的蛋白可启动非跨膜蛋白酪氨酸激酶活性。预计参与B细胞受体信号通路;适应性免疫反应;和肽基酪氨酸自磷酸化。预计在细胞凋亡过程的上游或内部起作用;细胞粘附;和磷酸化。预测位于核质和褶皱膜中。以多种结构表达,包括心血管系统;中枢神经系统;免疫系统;肺;和乳腺。与人 BMX(BMX 非受体酪氨酸激酶)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable non-membrane spanning protein tyrosine kinase activity. Predicted to be involved in B cell receptor signaling pathway; adaptive immune response; and peptidyl-tyrosine autophosphorylation. Predicted to act upstream of or within apoptotic process; cell adhesion; and phosphorylation. Predicted to be located in nucleoplasm and ruffle membrane. Is expressed in several structures, including cardiovascular system; central nervous system; immune system; lung; and mammary gland. Orthologous to human BMX (BMX non-receptor tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Bmx 基因产物(1)

mRNA Protein Name
NM_009759.4 NP_033889.2 cytoplasmic tyrosine-protein kinase BMX

Bmx 蛋白结构

PH_Btk

PH_Btk: cd01238 (24 - 150)

SH2_Tec_Bmx

SH2_Tec_Bmx: cd10399 (268 - 373)

PKc_like

PKc_like: cl21453 (391 - 646)

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  • 600
  • 655 a.a.
蛋白主名 其他名称

cytoplasmic tyrosine-protein kinase BMX

TYRO8 protein tyrosine kinase 8

bone marrow tyrosine kinase gene in chromosome X protein homolog

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bmx NCBI NCBI:660