2. Gene
  3. Cd19 - CD19 antigen Gene

Cd19 - CD19 antigen Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 12478 | 基因类型: protein coding

关于 Cd19

功能概要

Involved in several processes, including B-1 B cell differentiation; positive regulation of phosphatidylinositol 3-kinase activity; and positive regulation of release of sequestered calcium ion into cytosol. Acts upstream of or within B cell receptor signaling pathway. Located in external side of plasma membrane. Is integral component of plasma membrane. Is expressed in liver and spleen. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human CD19 (CD19 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd19 基因产物(2)

mRNA Protein Name
NM_001357091.2 NP_001344020.1 B-lymphocyte antigen CD19 isoform 2 precursor
NM_009844.3 NP_033974.2 B-lymphocyte antigen CD19 isoform 1 precursor
蛋白主名 其他名称

B-lymphocyte antigen CD19

differentiation antigen CD19

重组 Cd19 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74328 CD19 Protein, Mouse (HEK293, His) P25918 (G17-G287) ≥95%
HY-P77527 CD19 Protein, Mouse (Biotinylated, HEK293, His) P25918 (G17-G287) ≥95%

相关产品

Approval
抗体抑制剂 (3)
目录号 产品名 作用方式
纯度 是否罕见病
HY-P9963 Blinatumomab Inhibitor 98.78% 否
HY-P99113 Inebilizumab Inhibitor 99.00% 否
HY-P99338 Tisagenlecleucel / 否
Clinical Phase
抗体抑制剂 (5)
目录号 产品名 作用方式
纯度 Phase
HY-P99711 Loncastuximab Inhibitor 95.00% Phase 3
HY-P99761 Obexelimab Inhibitor 95.00% Phase 3
HY-P99285 Denintuzumab Inhibitor 95.00% Phase 2
HY-P99868 Duvortuxizumab ≥99.0% Phase 1
HY-P990017 Englumafusp alfa Inhibitor / Phase 1
Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-153084 CD19 CAR mRNA (Mouse) / 否
HY-153084A CD19 CAR mRNA (Human) / 否
HY-153233 CD19 car mRNA (Mouse)-LNP ≥90.0% 否
HY-153085 CD19 CAR circRNA / 否
HY-153234 CD19 car circRNA-LNP / 否
抗体抑制剂 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P99976 Anti-Mouse CD19 Antibody (1D3) Inhibitor 95.00% 否
HY-P99577 Taplitumomab paptox / 否
HY-P99914 Emfizatamab / 否
HY-P990729 Budoprutug / 否
HY-P990694 Zeripatamig / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd19 NCBI NCBI:930
Macaca fascicularis Cd19 NCBI NCBI:102145514
Macaca mulatta Cd19 NCBI NCBI:705211
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