1. Gene
  2. Cd24a - CD24a antigen Gene

Cd24a - CD24a antigen Gene

种属: Mus musculus

同用名: HSA; Cd24; Ly-52; nectadrin

基因 ID: 12484 | 基因类型: protein coding

关于 Cd24a

功能概要

Enables HSP70 protein binding activity; HSP90 protein binding activity; and carbohydrate binding activity. Involved in several processes, including Chemokine Receptor transport out of membrane raft; negative regulation of cytokine production; and regulation of inflammatory response to wounding. Acts upstream of or within several processes, including positive regulation of immune response; regulation of cell-cell adhesion; and regulation of lymphocyte activation. Located in cell projection membrane; external side of plasma membrane; and membrane raft. Is anchored component of external side of plasma membrane. Is expressed in several structures, including extraembryonic component; genitourinary system; hemolymphoid system; hindlimb; and retina. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human CD24 (CD24 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd24a 基因产物(1)

mRNA Protein Name
NM_009846.2 NP_033976.1 signal transducer CD24 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables Hsp70 protein binding IDA
IDA: 通过直接分析推断
19264983 MGI
enables Hsp90 protein binding IDA
IDA: 通过直接分析推断
19264983 MGI
enables carbohydrate binding IDA
IDA: 通过直接分析推断
15633604 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
7524641 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of B cell apoptotic process IDA
IDA: 通过直接分析推断
8920854 MGI
acts upstream of B cell proliferation IDA
IDA: 通过直接分析推断
8920854 MGI
acts upstream of CD4-positive, alpha-beta T cell proliferation IDA
IDA: 通过直接分析推断
8125140 MGI
acts upstream of CD4-positive, alpha-beta T cell proliferation IMP
IMP: 通过突变表型推断
15314074 MGI
acts upstream of T cell homeostatic proliferation IMP
IMP: 通过突变表型推断
15477346 MGI
acts upstream of or within apoptotic mitochondrial changes IDA
IDA: 通过直接分析推断
14707049 MGI
acts upstream of or within apoptotic nuclear changes IDA
IDA: 通过直接分析推断
14707049 MGI
acts upstream of or within apoptotic signaling pathway IDA
IDA: 通过直接分析推断
8920854 MGI
acts upstream of calcium-mediated signaling IDA
IDA: 通过直接分析推断
7613634 MGI
involved in cell migration IMP
IMP: 通过突变表型推断
16390867 MGI
acts upstream of or within cell surface receptor signaling pathway IDA
IDA: 通过直接分析推断
7613634 MGI
involved in chemokine receptor transport out of membrane raft IMP
IMP: 通过突变表型推断
16390867 MGI
involved in cholesterol homeostasis IMP
IMP: 通过突变表型推断
16390867 MGI
acts upstream of or within heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IDA
IDA: 通过直接分析推断
8145052 MGI
acts upstream of or within homotypic cell-cell adhesion IMP
IMP: 通过突变表型推断
7613634 MGI
acts upstream of integrin activation IDA
IDA: 通过直接分析推断
10601245 MGI
acts upstream of integrin activation IMP
IMP: 通过突变表型推断
10601245 MGI
acts upstream of or within leukocyte cell-cell adhesion IDA
IDA: 通过直接分析推断
7534304 MGI
acts upstream of or within leukocyte migration involved in inflammatory response IMP
IMP: 通过突变表型推断
15314074 MGI
acts upstream of or within negative regulation of B cell proliferation IDA
IDA: 通过直接分析推断
8920854 MGI
acts upstream of or within negative regulation of T cell homeostatic proliferation IMP
IMP: 通过突变表型推断
16769998 MGI
acts upstream of or within negative regulation of erythrocyte aggregation IMP
IMP: 通过突变表型推断
9028339 MGI
acts upstream of or within negative regulation of erythrocyte clearance IMP
IMP: 通过突变表型推断
9028339 MGI
involved in negative regulation of inflammatory response to wounding IPI
IPI: 通过物理相互作用推断
19264983 MGI
involved in negative regulation of interleukin-6 production IMP
IMP: 通过突变表型推断
19264983 MGI
involved in negative regulation of monocyte chemotactic protein-1 production IMP
IMP: 通过突变表型推断
19264983 MGI
acts upstream of or within negative regulation of neuroblast proliferation IMP
IMP: 通过突变表型推断
11978835 MGI
acts upstream of or within negative regulation of neurogenesis IMP
IMP: 通过突变表型推断
15737737 MGI
acts upstream of or within negative regulation of neuron differentiation IMP
IMP: 通过突变表型推断
15737737 MGI
involved in negative regulation of tumor necrosis factor production IMP
IMP: 通过突变表型推断
19264983 MGI
acts upstream of neuroblast proliferation IMP
IMP: 通过突变表型推断
11978835 MGI
acts upstream of or within neuromuscular synaptic transmission IGI
IGI: 通过遗传相互作用推断
16606832 MGI
acts upstream of or within neuromuscular synaptic transmission IMP
IMP: 通过突变表型推断
16606832 MGI
acts upstream of neuron projection development IDA
IDA: 通过直接分析推断
19458237 MGI
acts upstream of or within neuron projection development IDA
IDA: 通过直接分析推断
11283023 MGI
acts upstream of neuron projection development IGI
IGI: 通过遗传相互作用推断
19458237 MGI
acts upstream of or within neuron projection development IMP
IMP: 通过突变表型推断
11283023 MGI
acts upstream of peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
9177270 MGI
acts upstream of or within positive regulation of B cell apoptotic process IDA
IDA: 通过直接分析推断
8920854 MGI
acts upstream of or within positive regulation of CD4-positive, alpha-beta T cell proliferation IDA
IDA: 通过直接分析推断
8125140 MGI
acts upstream of or within positive regulation of CD4-positive, alpha-beta T cell proliferation IMP
IMP: 通过突变表型推断
15314074 MGI
acts upstream of or within positive regulation of T cell homeostatic proliferation IMP
IMP: 通过突变表型推断
15477346 MGI
acts upstream of or within positive regulation of T cell mediated immune response to tumor cell IDA
IDA: 通过直接分析推断
7774619 MGI
acts upstream of or within positive regulation of alpha-beta T cell proliferation IDA
IDA: 通过直接分析推断
1346270 MGI
acts upstream of or within positive regulation of alpha-beta T cell proliferation IMP
IMP: 通过突变表型推断
1385153 MGI
acts upstream of or within positive regulation of calcium-mediated signaling IDA
IDA: 通过直接分析推断
7613634 MGI
acts upstream of or within positive regulation of cell adhesion mediated by integrin IDA
IDA: 通过直接分析推断
10601245 MGI
acts upstream of or within positive regulation of cell adhesion mediated by integrin IMP
IMP: 通过突变表型推断
10601245 MGI
acts upstream of or within positive regulation of cell-cell adhesion IDA
IDA: 通过直接分析推断
7669058 MGI
acts upstream of or within positive regulation of cell-cell adhesion mediated by integrin IDA
IDA: 通过直接分析推断
7534304 MGI
acts upstream of or within positive regulation of inflammatory response to antigenic stimulus IMP
IMP: 通过突变表型推断
10791997 MGI
involved in positive regulation of inflammatory response to wounding IMP
IMP: 通过突变表型推断
19264983 MGI
acts upstream of or within positive regulation of integrin activation IDA
IDA: 通过直接分析推断
7534304 MGI
acts upstream of or within positive regulation of integrin activation IMP
IMP: 通过突变表型推断
10601245 MGI
acts upstream of or within positive regulation of neuron projection development IDA
IDA: 通过直接分析推断
19458237 MGI
acts upstream of or within positive regulation of neuron projection development IGI
IGI: 通过遗传相互作用推断
19458237 MGI
acts upstream of or within positive regulation of peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
9177270 MGI
acts upstream of or within pre-B cell differentiation IMP
IMP: 通过突变表型推断
7795661 MGI
acts upstream of or within regulation of B cell differentiation IMP
IMP: 通过突变表型推断
7795661 MGI
acts upstream of or within regulation of cell-cell adhesion IDA
IDA: 通过直接分析推断
8117278 MGI
acts upstream of or within regulation of cell-cell adhesion mediated by integrin IDA
IDA: 通过直接分析推断
8145052 MGI
involved in regulation of cytokine-mediated signaling pathway IMP
IMP: 通过突变表型推断
16390867 MGI
involved in response to molecule of bacterial origin IDA
IDA: 通过直接分析推断
15493995 MGI
acts upstream of or within synaptic vesicle endocytosis IMP
IMP: 通过突变表型推断
16606832 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
9324354 MGI
located in ciliary membrane IDA
IDA: 通过直接分析推断
11978835 MGI
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
1346270 MGI
located in membrane IDA
IDA: 通过直接分析推断
11283023 MGI
located in membrane raft IDA
IDA: 通过直接分析推断
15493995 MGI
located in microvillus membrane IDA
IDA: 通过直接分析推断
11978835 MGI
located in motile cilium IDA
IDA: 通过直接分析推断
35087169 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
11978835 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

signal transducer CD24

M1/69-J11D heat stable antigen

R13-Ag

X62 heat stable antigen

cluster of differentiation 24

heat stable antigen

lymphocyte antigen 52

重组 Cd24a 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72747 CD24 Protein, Mouse (HEK293, hFc) P24807 (N27-G53) ≥95%
HY-P78255 CD24 Protein, Mouse (27a.a, HEK293, mFc) P24807 (N27-G53) ≥95%

直系同源

种属 基因名 来源 基因 ID
Macaca fascicularis Cd24a NCBI
Rattus norvegicus Cd24a NCBI