1. Gene
  2. Entpd1 - ectonucleoside triphosphate diphosphohydrolase 1 Gene

Entpd1 - ectonucleoside triphosphate diphosphohydrolase 1 Gene

种属: Mus musculus

同用名: Cd39; NTPDase-1; 2610206B08Rik; E130009M23Rik

基因 ID: 12495 | 基因类型: protein coding

关于 Entpd1

功能概要

Enables adenosine-diphosphatase activity and nucleoside-triphosphatase activity. Involved in ADP catabolic process. Acts upstream of or within G protein-coupled receptor signaling pathway; platelet activation; and purine ribonucleoside diphosphate catabolic process. Located in basement membrane. Is active in external side of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and respiratory system. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 64. Orthologous to human ENTPD1 (ectonucleoside triphosphate diphosphohydrolase 1). [provided by Alliance of Genome Resources, Apr 2022]

Entpd1 基因产物(2)

mRNA Protein Name
NM_001304721.1 NP_001291650.1 ectonucleoside triphosphate diphosphohydrolase 1 isoform 1
NM_009848.4 NP_033978.1 ectonucleoside triphosphate diphosphohydrolase 1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ADP phosphatase activity IMP
IMP: 通过突变表型推断
17502665 MGI
enables nucleoside diphosphate phosphatase activity IDA
IDA: 通过直接分析推断
11929769 MGI
enables ribonucleoside triphosphate phosphatase activity IDA
IDA: 通过直接分析推断
11929769 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ADP catabolic process IMP
IMP: 通过突变表型推断
17502665 MGI
acts upstream of or within G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
11929769 MGI
acts upstream of or within platelet activation IDA
IDA: 通过直接分析推断
11929769 MGI
acts upstream of or within purine ribonucleoside diphosphate catabolic process IDA
IDA: 通过直接分析推断
11929769 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basement membrane IDA
IDA: 通过直接分析推断
11929769 MGI
is active in external side of plasma membrane IMP
IMP: 通过突变表型推断
17502665 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ectonucleoside triphosphate diphosphohydrolase 1

CD39 antigen

NTPDase 1

ecto-ATP diphosphohydrolase 1

ecto-ATPDase 1

ecto-ATPase 1

ectoapyrase

lymphoid cell activation antigen

重组 Entpd1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70727 CD39 Protein, Mouse (HEK293, His) P55772 (T38-I478) ≥95%
HY-P72898 CD39 Protein, Mouse (His) P55772 (T38-I478) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Entpd1 NCBI NCBI:953
Macaca mulatta Entpd1 NCBI