2. Gene
  3. PLK5 - polo like kinase 5 (inactive) Gene

PLK5 - polo like kinase 5 (inactive) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：马球样激酶 5 (非活性)

种属: Homo sapiens

同用名: PLK-5; PLK5P; SgK384ps

基因 ID: 126520 | 基因类型: protein coding

关于 PLK5

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:1,508,023-1,536,046 (from NCBI)

This gene has 10 transcripts (splice variants), 98 orthologues and 4 paralogues. Biased expression in testis (RPKM 2.5), endometrium (RPKM 1.6) and 3 other tissues.

功能概要

预测启用 ATP 结合活性和蛋白激酶活性。参与多个过程，包括对肿瘤细胞的防御反应；神经元投射发育的正向调节；和调节有丝分裂细胞周期的 G1/S 转换。位于细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable ATP binding activity and protein kinase activity. Involved in several processes, including defense response to tumor cell; positive regulation of neuron projection development; and regulation of G1/S transition of mitotic cell cycle. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PLK5 基因产物(3)

mRNA Protein Name
NM_001011716.1
NR_026557.1
NM_001243079.2 NP_001230008.1 inactive serine/threonine-protein kinase PLK5
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to growth factor stimulus IDA
IDA: 通过直接分析推断
21245385 GOA
involved in defense response to tumor cell IDA
IDA: 通过直接分析推断
21245385 GOA
involved in positive regulation of neuron projection development IDA
IDA: 通过直接分析推断
21245385 GOA
involved in regulation of G1/S transition of mitotic cell cycle IMP
IMP: 通过突变表型推断
21245385 GOA
involved in regulation of apoptotic process IMP
IMP: 通过突变表型推断
21245385 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
21245385 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

inactive serine/threonine-protein kinase PLK5

polo-like kinase 5, pseudogene

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10723 PLK5 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS10724 Plk5 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS10725 Plk5 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus PLK5 RGD RGD:1305038
Mus musculus PLK5 MGD MGI:3026984
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