1. Gene
  2. FCRLB - Fc receptor like B Gene

FCRLB - Fc receptor like B Gene

中文名称:Fc 受体样 B

种属: Homo sapiens

同用名: FcRY; FCRL2; FCRLY; FREB2; FCRLM2; FREB-2

基因 ID: 127943 | 基因类型: protein coding

关于 FCRLB

Cytogenetic location: 1q23.3 Genomic coordinates (GRCh38): 1:161,721,544-161,728,143 (from NCBI)

This gene has 6 transcripts (splice variants), 207 orthologues and 17 paralogues. Broad expression in kidney (RPKM 1.2), appendix (RPKM 0.8) and 23 other tissues.

功能概要

FCRL2 属于 Fc 受体家族。 Fc 受体通过其结合免疫球蛋白 (Ig) 恒定区的能力参与免疫球蛋白的吞噬作用、抗体依赖性细胞毒性、速发型超敏反应和转胞吞作用 (Chikaev 等人,2005 [PubMed 15676285]) 。[OMIM 提供,3 月 2008]

FCRL2 belongs to the Fc receptor family. Fc Receptors are involved in phagocytosis, antibody-dependent cell cytotoxicity, immediate hypersensitivity, and transcytosis of immunoglobulins via their ability to bind immunoglobulin (Ig) constant regions (Chikaev et al., 2005 [PubMed 15676285]).[supplied by OMIM, Mar 2008]

FCRLB 基因产物(6)

mRNA Protein Name
NM_001002901.4 NP_001002901.1 Fc receptor-like B isoform 1 precursor
NM_001288829.1 NP_001275758.1 Fc receptor-like B isoform 2 precursor
NM_001288830.1 NP_001275759.1 Fc receptor-like B isoform 3 precursor
NM_001288831.1 NP_001275760.1 Fc receptor-like B isoform 4 precursor
NM_001288832.1 NP_001275761.1 Fc receptor-like B isoform 5 precursor
NM_001320241.1 NP_001307170.1 Fc receptor-like B isoform 1 precursor
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15815692 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

FCRLB 蛋白结构

Ig_2

Ig_2: Immunoglobulin domain (22 - 98)

Ig_2

Ig_2: Immunoglobulin domain (105 - 172)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 426 a.a.
蛋白主名 其他名称

Fc receptor-like B

fc receptor homolog expressed in B cells protein 2

直系同源

种属 基因名 来源 基因 ID
Mus musculus FCRLB MGD MGI:3576487
Bos taurus FCRLB VGNC VGNC:28940
Rattus norvegicus FCRLB RGD RGD:1563018
Macaca mulatta FCRLB VGNC VGNC:106365
Canis familiaris FCRLB VGNC VGNC:53118
Felis catus FCRLB VGNC VGNC:62218