1. Gene
  2. Ddx3x - DEAD box helicase 3, X-linked Gene

Ddx3x - DEAD box helicase 3, X-linked Gene

种属: Mus musculus

同用名: Ddx3; Fin14; D1Pas1-rs2

基因 ID: 13205 | 基因类型: protein coding

关于 Ddx3x

功能概要

Enables primary miRNA binding activity. Involved in positive regulation of NLRP3 inflammasome complex assembly and stress granule assembly. Acts upstream of or within with a negative effect on primary miRNA processing. Located in cytoplasmic stress granule. Part of NLRP3 inflammasome complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability. Orthologous to human DDX3X (DEAD-box helicase 3 X-linked). [provided by Alliance of Genome Resources, Apr 2022]

Ddx3x 基因产物(1)

mRNA Protein Name
NM_010028.3 NP_034158.1 ATP-dependent RNA helicase DDX3X
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables primary miRNA binding IDA
IDA: 通过直接分析推断
28819115 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
18583960 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of NLRP3 inflammasome complex assembly IDA
IDA: 通过直接分析推断
31511697 MGI
acts upstream of or within negative effect primary miRNA processing IDA
IDA: 通过直接分析推断
28819115 MGI
acts upstream of or within negative effect primary miRNA processing IMP
IMP: 通过突变表型推断
28819115 MGI
involved in stress granule assembly IMP
IMP: 通过突变表型推断
31511697 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of NLRP3 inflammasome complex IDA
IDA: 通过直接分析推断
31511697 MGI
located in cytoplasmic stress granule IDA
IDA: 通过直接分析推断
31511697 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ATP-dependent RNA helicase DDX3X

D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 3

D1Pas1-related sequence 2

DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 3

DEAD box RNA helicase DEAD3

DEAD box protein 3, X-chromosomal

DEAD-box protein 3 (DEAD-box RNA

Ddx3x 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Ddx3x Q62167 TBK1 Homo sapiens Q9UHD2 18583960
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ddx3x NCBI NCBI:1654