2. Gene
  3. JMY - junction mediating and regulatory protein, p53 cofactor Gene

JMY - junction mediating and regulatory protein, p53 cofactor Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：连接介导和调节蛋白，p53 辅助因子

种属: Homo sapiens

同用名: WHAMM2; WHDC1L3

基因 ID: 133746 | 基因类型: protein coding

关于 JMY

Cytogenetic location: 5q14.1 Genomic coordinates (GRCh38): 5:79,236,131-79,327,211 (from NCBI)

This gene has 2 transcripts (splice variants), 250 orthologues and 2 paralogues. Ubiquitous expression in endometrium (RPKM 8.1), thyroid (RPKM 7.3) and 25 other tissues.

功能概要

预测启用 Arp2/3 复合物结合活性和转录共激活因子活性。预计参与多个过程，包括肌动蛋白成核； p53 类介质的内在凋亡信号通路；和转录调控，DNA 模板化。位于细胞前沿。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable Arp2/3 complex binding activity and transcription coactivator activity. Predicted to be involved in several processes, including actin nucleation; intrinsic apoptotic signaling pathway by p53 class mediator; and regulation of transcription, DNA-templated. Located in cell leading edge. [provided by Alliance of Genome Resources, Apr 2022]

JMY 基因产物(1)

mRNA Protein Name
NM_152405.5 NP_689618.4 junction-mediating and #NAME? protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables microtubule binding IDA
IDA: 通过直接分析推断
30420355 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
10518217 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to starvation IMP
IMP: 通过突变表型推断
30420355 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in autophagosome membrane IDA
IDA: 通过直接分析推断
30420355 GOA
located in cell leading edge IDA
IDA: 通过直接分析推断
19287377 GOA
located in cytoplasmic vesicle IDA
IDA: 通过直接分析推断
30420355 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

junction-mediating and -regulatory protein

WAS protein homology region 2 domain containing 1-like 3

JMY 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
JMY Q8N9B5 MDM2 Homo sapiens Q00987
Anti Bait CoIP
17170761
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Wiskott-Aldrich Syndrome

WAS

Eczema-Thrombocytopenia-Immunodeficiency Syndrome

Immunodeficiency 2

Aldrich Syndrome

Imd2

Wiskott-Aldrich Syndrome 1

Was1

Wiskott Syndrome

Wiskott Aldrich Syndrome

Eczema Thrombocytopenia Immunodeficiency Syndrome

Imd 2
Phacolytic Glaucoma
Hemoglobin H Disease

HBH

Hemoglobin H Disease, Nondeletional

Hemoglobin H Disease, Deletional

Alpha-Thalassemia Intermedia

Haemoglobin H Disease

Alpha-Thalassemia, Hemoglobin H Type

Hemoglobin H Disease, Deletional And Nondeletional

Alpha Thalassemia, Haemoglobin H Type

Alpha Thalassemia, Hemoglobin H Type

Haemoglobin H Disease, Deletional

Hbh Disease

Alpha-Thalassemia Hemoglobin H Type

Hemoglobin H Disease Deletional

Hemoglobin H Disease Non-Deletional

Alpha-Thalassemia

Alpha - /- - Or Mutational Forms Of Alpha-Thalassaemia

Alpha Thalassaemia Intermedia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07042 JMY Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris JMY VGNC VGNC:42191
Bos taurus JMY VGNC VGNC:30378
Felis catus JMY VGNC VGNC:63009
Rattus norvegicus JMY RGD RGD:1585601
Macaca mulatta JMY VGNC VGNC:84397
Mus musculus JMY MGD MGI:1913096
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z