1. Gene
  2. ADAT2 - adenosine deaminase tRNA specific 2 Gene

ADAT2 - adenosine deaminase tRNA specific 2 Gene

中文名称:腺苷脱氨酶 tRNA 特异性 2

种属: Homo sapiens

同用名: TAD2; DEADC1; dJ20N2; dJ20N2.1

基因 ID: 134637 | 基因类型: protein coding

关于 ADAT2

Cytogenetic location: 6q24.2 Genomic coordinates (GRCh38): 6:143,422,832-143,450,695 (from NCBI)

This gene has 3 transcripts (splice variants), 198 orthologues and 1 paralogue. Ubiquitous expression in skin (RPKM 2.8), lymph node (RPKM 2.6) and 25 other tissues.

功能概要

预测可启用 tRNA 特异性腺苷 34 脱氨酶活性。预测参与 tRNA 摆动腺苷到肌苷的编辑。预测位于核质中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable tRNA-specific adenosine-34 deaminase activity. Predicted to be involved in tRNA wobble adenosine to inosine editing. Predicted to be located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ADAT2 基因产物(2)

mRNA Protein Name
NM_001286259.2 NP_001273188.1 tRNA-specific adenosine deaminase 2 isoform b
NM_182503.3 NP_872309.2 tRNA-specific adenosine deaminase 2 isoform a

ADAT2 蛋白结构

dCMP_cyt_deam_1

dCMP_cyt_deam_1: Cytidine and deoxycytidylate deaminase zinc-binding region (21 - 125)

  • 0
  • 100
  • 191 a.a.
蛋白主名 其他名称

tRNA-specific adenosine deaminase 2

adenosine deaminase, tRNA-specific 2, TAD2 homolog

ADAT2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra ADAT2 Q7Z6V5 SMARCD1 Homo sapiens Q96GM5
Validated Y2H
32296183
Intra ADAT2 Q7Z6V5 ADAT3 Homo sapiens Q96EY9
Anti Tag CoIP
33961781
Intra ADAT2 Q7Z6V5 SPRED1 Homo sapiens Q7Z699
Y2H Array
32814053
Intra ADAT2 Q7Z6V5 SPRED1 Homo sapiens Q7Z699
Validated Y2H
32814053
Intra ADAT2 Q7Z6V5 SPRED1 Homo sapiens Q7Z699
Y2H Pooling
32814053
Intra ADAT2 Q7Z6V5 SGTB Homo sapiens Q96EQ0
Y2H Array
32296183
Intra ADAT2 Q7Z6V5 SGTB Homo sapiens Q96EQ0
Y2H Prey Pooling
32296183
Intra ADAT2 Q7Z6V5 SGTB Homo sapiens Q96EQ0
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta ADAT2 VGNC VGNC:69490
Felis catus ADAT2 VGNC VGNC:59609
Bos taurus ADAT2 VGNC VGNC:25638
Rattus norvegicus ADAT2 RGD RGD:1309642
Mus musculus ADAT2 MGD MGI:1914007
Canis familiaris ADAT2 VGNC VGNC:37614