1. Gene
  2. Ebf2 - early B cell factor 2 Gene

Ebf2 - early B cell factor 2 Gene

种属: Mus musculus

同用名: OE-3; EBF-2; Mmot1; O/E-3; D14Ggc1e

基因 ID: 13592 | 基因类型: protein coding

关于 Ebf2

功能概要

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in positive regulation of cold-induced thermogenesis and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including adipose tissue development; brown fat cell differentiation; and positive regulation of chromatin binding activity. Predicted to be located in nucleus. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; limb mesenchyme; and sensory organ. Orthologous to human EBF2 (EBF transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Ebf2 基因产物(3)

mRNA Protein Name
NM_001276387.1 NP_001263316.1 transcription factor COE2
NM_001360202.1 NP_001347131.1 transcription factor COE2
NM_010095.6 NP_034225.1 transcription factor COE2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
9211912 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
12139918 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
12139918 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
23499423 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12139918 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

transcription factor COE2

MET-mesencephalon-olfactory TF1

MET-mesencephalon-olfactory transcription factor 1

Olf-1/EBF-like 3

metencephalon-mesencephalon-olfactory transcription factor 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ebf2 NCBI NCBI:64641