2. Gene
  3. Eda - ectodysplasin-A Gene

Eda - ectodysplasin-A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ta; Ed1; HED; EDA1; XLHED; tabby; Eda-A1; Eda-A2; Tnlg7c

基因 ID: 13607 | 基因类型: protein coding

关于 Eda

功能概要

Predicted to enable death receptor agonist activity and death receptor binding activity. Acts upstream of or within several processes, including animal organ development; cell-matrix adhesion; and positive regulation of signal transduction. Located in apical part of cell and endoplasmic reticulum membrane. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system; brain; future brain; nasal gland epithelium; and skin. Used to study hypohidrotic ectodermal dysplasia. Human ortholog(s) of this gene implicated in ectodermal dysplasia 1 and tooth agenesis. Orthologous to human EDA (ectodysplasin A). [provided by Alliance of Genome Resources, Apr 2022]

Eda 基因产物(9)

mRNA Protein Name
NM_001177937.1 NP_001171408.1 ectodysplasin-A isoform 2
NM_001177938.1 NP_001171409.1 ectodysplasin-A isoform 3
NM_001177939.1 NP_001171410.1 ectodysplasin-A isoform 4
NM_001177940.1 NP_001171411.1 ectodysplasin-A isoform 5
NM_001177941.1 NP_001171412.1 ectodysplasin-A isoform 6
NM_001177942.1 NP_001171413.1 ectodysplasin-A isoform 7
NM_001177943.1 NP_001171414.1 ectodysplasin-A isoform 8
NM_001177944.1 NP_001171415.1 ectodysplasin-A isoform 8
NM_010099.2 NP_034229.1 ectodysplasin-A isoform 1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of canonical Wnt signaling pathway IMP
IMP: 通过突变表型推断
19619491 MGI
acts upstream of or within cell-matrix adhesion IDA
IDA: 通过直接分析推断
10534613 MGI
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
17673451 MGI
acts upstream of or within hair follicle development IGI
IGI: 通过遗传相互作用推断
18689798 MGI
acts upstream of or within hair follicle development IMP
IMP: 通过突变表型推断
544312 MGI
acts upstream of or within hair follicle placode formation IGI
IGI: 通过遗传相互作用推断
19619491 MGI
acts upstream of or within odontogenesis of dentin-containing tooth IMP
IMP: 通过突变表型推断
5893447 MGI
acts upstream of or within pigmentation IMP
IMP: 通过突变表型推断
4561716 MGI
acts upstream of or within positive regulation of canonical NF-kappaB signal transduction IMP
IMP: 通过突变表型推断
18689798 MGI
acts upstream of or within positive regulation of canonical Wnt signaling pathway IMP
IMP: 通过突变表型推断
19619491 MGI
acts upstream of or within positive regulation of gene expression IDA
IDA: 通过直接分析推断
18508042 MGI
acts upstream of or within positive regulation of non-canonical NF-kappaB signal transduction IDA
IDA: 通过直接分析推断
12629675 MGI
acts upstream of or within salivary gland cavitation IDA
IDA: 通过直接分析推断
12629675 MGI
acts upstream of or within skin development IMP
IMP: 通过突变表型推断
17673451 MGI
acts upstream of or within trachea gland development IMP
IMP: 通过突变表型推断
15973734 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical part of cell IDA
IDA: 通过直接分析推断
12629675 MGI
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
10534613 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
10534613 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ectodysplasin-A

EDA protein homolog

tumor necrosis factor ligand 7c

相关产品

Pre-clinical Phase
生物活性分子 (15)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N2587 Irigenin 99.84% 否
HY-130893 Biotin-EDA 97.49% 否
HY-D1603 BODIPY FL-EDA 99.23% 否
HY-147097A EDA-DA TFA ≥95.0% 否
HY-126688 Mal-C2-Gly3-EDA-PNU-159682 93.43% 否
HY-114346A BODIPY FL EDA free base / 否
HY-125810 4'-Ethynyl-2'-deoxyadenosine Inhibitor / 否
HY-126673 Mal-C2-Gly3-EDA / 否
HY-145078 PNU-EDA-Gly5 / 否
HY-147097 EDA-DA / 否
HY-D1395 RH-EDA / 否
HY-RS04151 EDA Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS04152 EDA2R Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-151829 Fmoc-L-Asn(EDA-N3)-OH / 否
HY-151842 Fmoc-EDA-N3 / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Eda NCBI NCBI:1896
Macaca fascicularis Eda NCBI NCBI:102126767
Rattus norvegicus Eda NCBI NCBI:302424
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