2. Gene
  3. Efna1 - ephrin A1 Gene

Efna1 - ephrin A1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: B61; Efl1; Epl1; Eplg1; Lerk1

基因 ID: 13636 | 基因类型: protein coding

关于 Efna1

功能概要

Enables Ephrin Receptor binding activity. Involved in several processes, including heart valve morphogenesis; negative regulation of dendritic spine morphogenesis; and regulation of blood vessel endothelial cell migration. Acts upstream of or within several processes, including Ephrin Receptor signaling pathway; nervous system development; and regulation of MAPK cascade. Is anchored component of plasma membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Orthologous to human EFNA1 (ephrin A1). [provided by Alliance of Genome Resources, Apr 2022]

Efna1 基因产物(2)

mRNA Protein Name
NM_001162425.1 NP_001155897.1 ephrin-A1 isoform 2
NM_010107.4 NP_034237.3 ephrin-A1 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ephrin receptor binding IPI
IPI: 通过物理相互作用推断
22568954 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
22036564 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in aortic valve morphogenesis IMP
IMP: 通过突变表型推断
20960543 MGI
involved in endocardial cushion to mesenchymal transition involved in heart valve formation IMP
IMP: 通过突变表型推断
20960543 MGI
acts upstream of or within ephrin receptor signaling pathway IDA
IDA: 通过直接分析推断
14988728 MGI
involved in ephrin receptor signaling pathway IDA
IDA: 通过直接分析推断
17143272 MGI
involved in mitral valve morphogenesis IMP
IMP: 通过突变表型推断
20960543 MGI
acts upstream of or within negative regulation of MAPK cascade IDA
IDA: 通过直接分析推断
16547242 MGI
involved in negative regulation of dendritic spine morphogenesis IDA
IDA: 通过直接分析推断
17143272 MGI
involved in negative regulation of epithelial to mesenchymal transition IMP
IMP: 通过突变表型推断
20960543 MGI
acts upstream of or within negative regulation of thymocyte apoptotic process IDA
IDA: 通过直接分析推断
16547242 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
20960543 MGI
acts upstream of or within neuron differentiation IDA
IDA: 通过直接分析推断
15145949 MGI
acts upstream of or within notochord formation IGI
IGI: 通过遗传相互作用推断
11287184 MGI
acts upstream of or within positive regulation of MAPK cascade IDA
IDA: 通过直接分析推断
15145949 MGI
involved in regulation of angiogenesis IDA
IDA: 通过直接分析推断
16782872 MGI
acts upstream of or within regulation of axonogenesis IDA
IDA: 通过直接分析推断
14988728 MGI
involved in regulation of blood vessel endothelial cell migration IDA
IDA: 通过直接分析推断
16782872 MGI
involved in regulation of peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
17143272 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
18794797 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ephrin-A1

EPH-related receptor tyrosine kinase ligand 1

immediate early response protein B61

重组 Efna1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70373 Ephrin-A1/EFNA1 Protein, Mouse (HEK293, Fc-His) P52793 (D19-S182) ≥95%
HY-P73024 Ephrin-A1/EFNA1 Protein, Mouse (HEK293, His) P52793 (D19-S182) ≥95%
HY-P75234 Ephrin-A1/EFNA1 Protein, Mouse (HEK293, Fc) P52793 (D19-S182) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04192 EFNA1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Efna1 NCBI NCBI:1942
Rattus norvegicus Efna1 NCBI NCBI:94268
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