2. Gene
  3. Efnb3 - ephrin B3 Gene

Efnb3 - ephrin B3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Epl8; EFL-6; ELF-3; Elk-L3; LERK-8; NLERK-2

基因 ID: 13643 | 基因类型: protein coding

关于 Efnb3

功能概要

Predicted to enable Ephrin Receptor binding activity. Involved in negative regulation of axonogenesis and trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission. Acts upstream of or within T cell costimulation; adult walking behavior; and axon choice point recognition. Located in glutamatergic synapse and hippocampal mossy fiber to CA3 synapse. Is integral component of presynaptic membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Used to study movement disease. Orthologous to human EFNB3 (ephrin B3). [provided by Alliance of Genome Resources, Apr 2022]

Efnb3 基因产物(1)

mRNA Protein Name
NM_007911.5 NP_031937.1 ephrin-B3 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18632560 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within T cell costimulation IDA
IDA: 通过直接分析推断
15599401 MGI
acts upstream of or within adult walking behavior IMP
IMP: 通过突变表型推断
11182083 MGI
acts upstream of or within axon choice point recognition IMP
IMP: 通过突变表型推断
11182083 MGI
acts upstream of or within axon guidance IMP
IMP: 通过突变表型推断
11731465 MGI
involved in negative regulation of axonogenesis IDA
IDA: 通过直接分析推断
12383247 MGI
involved in trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission IDA
IDA: 通过直接分析推断
16571754 MGI
involved in trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission IMP
IMP: 通过突变表型推断
16571754 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
16571754 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
16571754 MGI
is active in hippocampal mossy fiber to CA3 synapse IDA
IDA: 通过直接分析推断
16571754 MGI
is active in hippocampal mossy fiber to CA3 synapse IMP
IMP: 通过突变表型推断
16571754 MGI
is active in presynaptic membrane IDA
IDA: 通过直接分析推断
16571754 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ephrin-B3

重组 Efnb3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75228 Ephrin B3 Protein, Mouse (HEK293, His) O35393 (L28-A227) ≥95%
HY-P75229 Ephrin B3 Protein, Mouse (HEK293, hFc) O35393 (L28-A227) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04199 EFNB3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Efnb3 NCBI NCBI:1949
Rattus norvegicus Efnb3 NCBI NCBI:360546
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