2. Gene
  3. Epha3 - Eph receptor A3 Gene

Epha3 - Eph receptor A3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: EK4; Hek; Cek4; ETK1; End3; Hek4; Mek4; Tyro4

基因 ID: 13837 | 基因类型: protein coding

关于 Epha3

功能概要

Enables Ephrin Receptor activity and growth factor binding activity. Involved in several processes, including axonal fasciculation; Ephrin Receptor signaling pathway; and synaptic membrane adhesion. Acts upstream of or within cellular response to follicle-stimulating hormone stimulus; negative regulation of neuron projection development; and regulation of cell migration. Located in GABA-ergic synapse. Is active in presynapse. Is expressed in several structures, including alimentary system; branchial arch; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in pancreatic Cancer. Orthologous to human EphA3 (EPH receptor A3). [provided by Alliance of Genome Resources, Apr 2022]

Epha3 基因产物(2)

mRNA Protein Name
NM_001362452.1 NP_001349381.1 ephrin type-A receptor 3 isoform 2 precursor
NM_010140.4 NP_034270.1 ephrin type-A receptor 3 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ephrin receptor activity IDA
IDA: 通过直接分析推断
15145949 MGI
enables growth factor binding IPI
IPI: 通过物理相互作用推断
22568954 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
19505147 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell migration IMP
IMP: 通过突变表型推断
17046737 MGI
acts upstream of or within cellular response to follicle-stimulating hormone stimulus IDA
IDA: 通过直接分析推断
23242526 MGI
involved in endocardial cushion development IMP
IMP: 通过突变表型推断
17046737 MGI
involved in ephrin receptor signaling pathway IDA
IDA: 通过直接分析推断
21135139 MGI
involved in fasciculation of motor neuron axon IMP
IMP: 通过突变表型推断
18403711 MGI
involved in fasciculation of sensory neuron axon IMP
IMP: 通过突变表型推断
21791286 MGI
NOT involved in motor neuron axon guidance IMP
IMP: 通过突变表型推断
17046737 MGI
acts upstream of or within negative regulation of neuron projection development IDA
IDA: 通过直接分析推断
19505147 MGI
acts upstream of or within regulation of cell migration IGI
IGI: 通过遗传相互作用推断
19505147 MGI
involved in regulation of epithelial to mesenchymal transition IMP
IMP: 通过突变表型推断
17046737 MGI
involved in synaptic membrane adhesion IDA
IDA: 通过直接分析推断
22275477 MGI
involved in synaptic membrane adhesion IMP
IMP: 通过突变表型推断
22275477 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
22275477 MGI
is active in GABA-ergic synapse IMP
IMP: 通过突变表型推断
22275477 MGI
is active in presynapse IDA
IDA: 通过直接分析推断
22275477 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ephrin type-A receptor 3

EPH-like kinase 4

tyrosine-protein kinase TYRO4

tyrosine-protein kinase receptor ETK1

重组 Epha3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75738 EphA3 Protein, Mouse (sf9) Q8BRB1 (G569-V984) ≥95%
HY-P75739 EphA3 Protein, Mouse (sf9, His-GST) Q8BRB1 (G569-V984) ≥95%
HY-P75740 EphA3 Protein, Mouse (HEK293, Fc) Q8BRB1 (M1-H541) ≥95%
HY-P75741 EphA3 Protein, Mouse (HEK293, His) Q8BRB1 (E21-H541) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-163835 UniPR1454 Antagonist / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Epha3 NCBI NCBI:2042
Canis familiaris Epha3 NCBI NCBI:487930
Rattus norvegicus Epha3 NCBI NCBI:29210
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z