2. Gene
  3. F2rl2 - coagulation factor II (thrombin) receptor-like 2 Gene

F2rl2 - coagulation factor II (thrombin) receptor-like 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：凝血因子 II (凝血酶) 受体样 2

种属: Mus musculus

同用名: PAR3; F730031A08

基因 ID: 14064 | 基因类型: protein coding

关于 F2rl2

Chromosome 13: 95,833,361-95,839,247 forward strand.GRCm39:CM001006.3

This gene has 1 transcript (splice variant), 262 orthologues, 16 paralogues and is associated with 3 phenotypes. Biased expression in liver E14.5 (RPKM 6.6), spleen adult (RPKM 5.4) and 8 other tissues.

功能概要

预计该基因编码的蛋白可启动 G 蛋白偶联受体活性。预计参与磷脂酶 C 激活 G 蛋白偶联信号通路中 Rho 蛋白信号转导的正向调节和胞质钙离子浓度的正向调节。预计在血液凝固和信号转导的上游或内部起作用。位于顶端质膜。以多种结构表达，包括中枢神经系统；肝;视网膜；皮肤;和脾脏。与人 F2RL2（凝血因子 II 凝血酶受体样 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of cytosolic calcium ion concentration involved in Phospholipase C-activating G protein-coupled signaling pathway. Predicted to act upstream of or within blood coagulation and signal transduction. Located in apical plasma membrane. Is expressed in several structures, including central nervous system; liver; retina; skin; and spleen. Orthologous to human F2RL2 (coagulation factor II Thrombin receptor like 2). [provided by Alliance of Genome Resources, Apr 2022]

F2rl2 基因产物(1)

mRNA Protein Name
NM_010170.4 NP_034300.3 proteinase-activated receptor 3 precursor

F2rl2 蛋白结构

7tm_GPCRs

7tm_GPCRs: cd14964 (95 - 119)

7tm_GPCRs

7tm_GPCRs: cl28897 (95 - 365)

7tm_GPCRs

7tm_GPCRs: cd14964 (127 - 148)

7tm_GPCRs

7tm_GPCRs: cd14964 (165 - 187)

7tm_GPCRs

7tm_GPCRs: cd14964 (210 - 226)

7tm_GPCRs

7tm_GPCRs: cd14964 (258 - 281)

7tm_GPCRs

7tm_GPCRs: cd14964 (298 - 320)

7tm_GPCRs

7tm_GPCRs: cd14964 (335 - 360)

  • 0
  • 100
  • 200
  • 300
  • 369 a.a.
蛋白主名 其他名称

proteinase-activated receptor 3

PAR-3

Proteinase activated receptor 3 precursor (PAR-3) (Thrombin receptor-like 2) (Coagulation factor II receptor-like 2)

coagulation factor II receptor-like 2

protease-activated receptor 3

thrombin receptor-like 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04637 F2RL2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS04638 F2rl2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS04639 F2rl2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens F2rl2 NCBI NCBI:2151
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