1. Gene
  2. Fgf18 - fibroblast growth factor 18 Gene

Fgf18 - fibroblast growth factor 18 Gene

种属: Mus musculus

同用名: Fgf6a; FGF-18; D130055P09Rik

基因 ID: 14172 | 基因类型: protein coding

关于 Fgf18

功能概要

Predicted to enable growth factor activity; type 1 Fibroblast Growth Factor receptor binding activity; and type 2 Fibroblast Growth Factor receptor binding activity. Acts upstream of or within several processes, including positive regulation of chondrocyte differentiation; positive regulation of signal transduction; and skeletal system development. Predicted to be located in nucleolus. Predicted to be active in cytoplasm and extracellular space. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; sensory organ; and skeleton. Orthologous to human FGF18 (Fibroblast Growth Factor 18). [provided by Alliance of Genome Resources, Apr 2022]

Fgf18 基因产物(1)

mRNA Protein Name
NM_008005.2 NP_032031.1 fibroblast growth factor 18 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
11741978 MGI
acts upstream of or within angiogenesis IMP
IMP: 通过突变表型推断
17014841 MGI
acts upstream of cell population proliferation IMP
IMP: 通过突变表型推断
17014841 MGI
acts upstream of or within chondrocyte development IMP
IMP: 通过突变表型推断
17014841 MGI
acts upstream of chondrocyte differentiation IGI
IGI: 通过遗传相互作用推断
15781473 MGI
acts upstream of or within endochondral ossification IMP
IMP: 通过突变表型推断
17014841 MGI
acts upstream of or within fibroblast growth factor receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
15781473 MGI
acts upstream of or within intramembranous ossification IMP
IMP: 通过突变表型推断
17014841 MGI
acts upstream of or within lung development IMP
IMP: 通过突变表型推断
15336546 MGI
acts upstream of or within ossification IMP
IMP: 通过突变表型推断
11937493 MGI
acts upstream of or within positive regulation of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
11741978 MGI
acts upstream of or within positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
17014841 MGI
acts upstream of or within positive regulation of chondrocyte differentiation IGI
IGI: 通过遗传相互作用推断
15781473 MGI
acts upstream of or within positive regulation of vascular endothelial growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
17014841 MGI
acts upstream of vascular endothelial growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
17014841 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

fibroblast growth factor 18

fibroblast growth factor 6a

zFGF5

重组 Fgf18 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7171 FGF-18 Protein, Mouse O89101 (E28-G207) ≥95%
HY-P75192 FGF-18 Protein, Mouse (HEK293, His) O89101 (E28-G207) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fgf18 NCBI NCBI:8817
Rattus norvegicus Fgf18 NCBI NCBI:29369