2. Gene
  3. Gab1 - growth factor receptor bound protein 2-associated protein 1 Gene

Gab1 - growth factor receptor bound protein 2-associated protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 14388 | 基因类型: protein coding

关于 Gab1

功能概要

Involved in positive regulation of cell migration by vascular endothelial growth factor signaling pathway. Acts upstream of or within several processes, including cell surface receptor signaling pathway; labyrinthine layer development; and positive regulation of MAP kinase activity. Located in cytoplasm. Is expressed in several structures, including brain; genitourinary system; heart; liver; and lung. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 26. Orthologous to human GAB1 (GRB2 associated binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Gab1 基因产物(2)

mRNA Protein Name
NM_001301298.1 NP_001288227.1 GRB2-associated-binding protein 1 isoform 1
NM_021356.2 NP_067331.2 GRB2-associated-binding protein 1 isoform 2
蛋白主名 其他名称

GRB2-associated-binding protein 1

GRB2-associated binder 1

Gab1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Gab1 Q9QYY0 Grb2 Mus musculus Q60631
Y2H
10871282
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Approval
生物活性分子 (4)
目录号 产品名 作用方式
纯度 是否罕见病
HY-13404 Capmatinib 99.92% 是
HY-13404C Capmatinib dihydrochloride hydrate 99.78% 是
HY-13404B Capmatinib hydrochloride 99.60% 否
HY-13404A Capmatinib dihydrochloride / 否
Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05197 GAB1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gab1 NCBI NCBI:2549
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