2. Gene
  3. CSNK1G3 - casein kinase 1 gamma 3 Gene

CSNK1G3 - casein kinase 1 gamma 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：酪蛋白激酶 1 γ 3

种属: Homo sapiens

同用名: CSNK1G3L; CKI-gamma 3

基因 ID: 1456 | 基因类型: protein coding

关于 CSNK1G3

Cytogenetic location: 5q23.2 Genomic coordinates (GRCh38): 5:123,512,177-123,617,049 (from NCBI)

This gene has 11 transcripts (splice variants), 127 orthologues and 12 paralogues. Ubiquitous expression in colon (RPKM 8.2), small intestine (RPKM 7.3) and 25 other tissues.

功能概要

该基因编码丝氨酸/苏氨酸蛋白激酶家族的一个成员，可使酪蛋白和其他酸性蛋白磷酸化。非洲爪蛙中的一种相关蛋白参与了 Wnt/β-连环蛋白信号的传递。已经观察到该基因编码多种亚型的可变剪接转录物变体。[RefSeq 提供，2012 年 7 月]

This gene encodes a member of a family of serine/threonine protein kinases that phosphorylate caseins and Other acidic proteins. A related protein in the African clawed frog participates in the transmission of Wnt/beta-catenin signaling. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

CSNK1G3 基因产物(16)

mRNA Protein Name
NM_001031812.4 NP_001026982.1 casein kinase I isoform gamma-3 isoform 2
NM_001044723.2 NP_001038188.1 casein kinase I isoform gamma-3 isoform 4
NM_001270572.1 NP_001257501.1 casein kinase I isoform gamma-3 isoform 5
NM_001270573.2 NP_001257502.1 casein kinase I isoform gamma-3 isoform 6
NM_001270574.2 NP_001257503.1 casein kinase I isoform gamma-3 isoform 7
NM_001364140.2 NP_001351069.1 casein kinase I isoform gamma-3 isoform 8
NM_001364141.2 NP_001351070.1 casein kinase I isoform gamma-3 isoform 9
NM_001364143.2 NP_001351072.1 casein kinase I isoform gamma-3 isoform 10
NM_001364144.2 NP_001351073.1 casein kinase I isoform gamma-3 isoform 11
NM_001364145.2 NP_001351074.1 casein kinase I isoform gamma-3 isoform 12
NM_001364146.2 NP_001351075.1 casein kinase I isoform gamma-3 isoform 13
NM_001364147.2 NP_001351076.1 casein kinase I isoform gamma-3 isoform 14
NM_001364148.2 NP_001351077.1 casein kinase I isoform gamma-3 isoform 15
NM_001364149.2 NP_001351078.1 casein kinase I isoform gamma-3 isoform 6
NM_001364150.2 NP_001351079.1 casein kinase I isoform gamma-3 isoform 6
NM_004384.5 NP_004375.2 casein kinase I isoform gamma-3 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
25500533 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CSNK1G3 蛋白结构

Pkinase

Pkinase: Protein kinase domain (43 - 297)

CK1gamma_C

CK1gamma_C: Casein kinase 1 gamma C terminal (328 - 417)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 447 a.a.
蛋白主名 其他名称

casein kinase I isoform gamma-3

casein kinase I

CSNK1G3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
CSNK1G3 Q9Y6M4 CSNK1G1 Homo sapiens Q9HCP0
Anti Tag CoIP
33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Sarcosinemia

Sarcosine Dehydrogenase Complex Deficiency

Sard Deficiency

Sardh Deficiency

SARCOS

Hypersarcosinemia

Sardhd

Demethylation Defect Of N-Methylglycine
Lissencephaly 8

LIS8
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03250 CSNK1G3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus CSNK1G3 MGD MGI:1917675
Felis catus CSNK1G3 VGNC VGNC:97392
Canis familiaris CSNK1G3 VGNC VGNC:39669
Bos taurus CSNK1G3 VGNC VGNC:27768
Rattus norvegicus CSNK1G3 RGD RGD:621408
Macaca mulatta CSNK1G3 VGNC VGNC:81384
Others CSNK1G3 NCBI
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