Ptgdr2 - prostaglandin D2 receptor 2 Gene

中文名称：前列腺素 D2 受体 2

种属: Mus musculus

同用名: Crth2; Gpr44; Grp45

关于 Ptgdr2

功能概要

该基因编码的蛋白可启动前列腺素 D 受体活性；前列腺素 F 受体活性；和前列腺素 J 受体活性。作用于多个过程的上游或内部，包括腺苷酸环化酶抑制 G 蛋白偶联受体信号通路；雄性生殖细胞增殖的负调节； G 蛋白偶联受体信号通路的正调控。预测位于质膜中。预计是膜的组成部分。预计在神经元投射中活跃。预计是质膜的组成部分。该基因的人类直系同源物与哮喘有关。与人类 PTGDR2（前列腺素 D2 受体 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables prostaglandin D receptor activity; prostaglandin F receptor activity; and prostaglandin J receptor activity. Acts upstream of or within several processes, including adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; negative regulation of male germ cell proliferation; and positive regulation of G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in neuron projection. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in asthma. Orthologous to human PTGDR2 (prostaglandin D2 receptor 2). [provided by Alliance of Genome Resources, Apr 2022]