1. Gene
  2. Gucy2c - guanylate cyclase 2c Gene

Gucy2c - guanylate cyclase 2c Gene

种属: Mus musculus

同用名: Gcc; GC-C

基因 ID: 14917 | 基因类型: protein coding

关于 Gucy2c

功能概要

Enables Guanylate Cyclase activity. Acts upstream of or within regulation of cell population proliferation and response to toxic substance. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in alimentary system and liver. Used to study abdominal obesity-metabolic syndrome and obesity. Human ortholog(s) of this gene implicated in congenital diarrhea 6. Orthologous to human GUCY2C (Guanylate Cyclase 2C). [provided by Alliance of Genome Resources, Apr 2022]

Gucy2c 基因产物(2)

mRNA Protein Name
NM_001127318.1 NP_001120790.1 guanylyl cyclase C isoform 1 precursor
NM_145067.3 NP_659504.2 guanylyl cyclase C isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables guanylate cyclase activity IMP
IMP: 通过突变表型推断
9294128 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within regulation of cell population proliferation IGI
IGI: 通过遗传相互作用推断
17681179 MGI
acts upstream of or within response to toxic substance IMP
IMP: 通过突变表型推断
9294128 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

guanylyl cyclase C

STA receptor

heat-stable enterotoxin receptor

intestinal guanylate cyclase

重组 Gucy2c 蛋白

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gucy2c NCBI NCBI:2984
Canis familiaris Gucy2c NCBI NCBI:486671
Macaca fascicularis Gucy2c NCBI NCBI:102130850
Rattus norvegicus Gucy2c NCBI NCBI:25711