2. Gene
  3. Cfb - complement factor B Gene

Cfb - complement factor B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Bf; C2; Fb; H2-Bf

基因 ID: 14962 | 基因类型: protein coding

关于 Cfb

功能概要

Predicted to enable serine-type endopeptidase activity. Acts upstream of or within complement activation, alternative pathway. Predicted to be located in extracellular region. Is expressed in embryo and liver lobe. Human ortholog(s) of this gene implicated in several diseases, including atypical hemolytic-uremic syndrome; autoimmune disease (multiple); eye disease (multiple); glomerulonephritis (multiple); and sickle cell anemia. Orthologous to human CFB (Complement Factor B). [provided by Alliance of Genome Resources, Apr 2022]

Cfb 基因产物(3)

mRNA Protein Name
NM_001142706.2 NP_001136178.1 complement factor B isoform 2 precursor
NM_001402875.1 NP_001389804.1 complement factor B isoform 3 precursor
NM_008198.3 NP_032224.2 complement factor B isoform 1 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within complement activation, alternative pathway IGI
IGI: 通过遗传相互作用推断
27564415 MGI
acts upstream of or within complement activation, alternative pathway IMP
IMP: 通过突变表型推断
9238044 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

complement factor B

C3/C5 convertase

Factor B

alternative-complement pathway C3/C5 convertase

complement component 2 (within H-2S)

histocompatibility 2, complement component factor B

properdin

重组 Cfb 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72137 Complement Factor B/CFB Protein, Mouse (His) P04186 (T23-L761) ≥95%

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-148370 IONIS-FB-LRx Inhibitor / Phase 2
Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-148370A IONIS-FB-LRx sodium Inhibitor 93.90% 否
HY-RS02557 CFB Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cfb NCBI NCBI:629
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