2. Gene
  3. IGSF11 - immunoglobulin superfamily member 11 Gene

IGSF11 - immunoglobulin superfamily member 11 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：免疫球蛋白超家族成员 11

种属: Homo sapiens

同用名: CT119; VSIG3; BTIGSF; Igsf13; BT-IgSF; CXADRL1

基因 ID: 152404 | 基因类型: protein coding

关于 IGSF11

Cytogenetic location: 3q13.32 Genomic coordinates (GRCh38): 3:118,900,557-119,146,020 (from NCBI)

This gene has 10 transcripts (splice variants), 205 orthologues and 14 paralogues. Biased expression in testis (RPKM 12.0), brain (RPKM 8.3) and 4 other tissues.

功能概要

IGSF11 是一种免疫球蛋白 (Ig) 超家族成员，优先在大脑和睾丸中表达。它与柯萨奇病毒和腺病毒受体 (CXADR; MIM 602621) 和内皮细胞选择性粘附分子 (ESAM) 具有显着的同源性。[OMIM 提供，2005 年 4 月]

IGSF11 is an immunoglobulin (Ig) superfamily member that is preferentially expressed in brain and testis. It shares significant homology with coxsackievirus and adenovirus receptor (CXADR; MIM 602621) and endothelial cell-selective adhesion molecule (ESAM).[supplied by OMIM, Apr 2005]

IGSF11 基因产物(11)

mRNA Protein Name
NM_001015887.3 NP_001015887.1 immunoglobulin superfamily member 11 isoform b precursor
NM_001353318.2 NP_001340247.1 immunoglobulin superfamily member 11 isoform c
NM_001353319.2 NP_001340248.1 immunoglobulin superfamily member 11 isoform d
NM_001353320.2 NP_001340249.1 immunoglobulin superfamily member 11 isoform a precursor
NM_001353321.2 NP_001340250.1 immunoglobulin superfamily member 11 isoform e precursor
NM_001353322.2 NP_001340251.1 immunoglobulin superfamily member 11 isoform f precursor
NM_001353323.2 NP_001340252.1 immunoglobulin superfamily member 11 isoform g precursor
NM_001353324.2 NP_001340253.1 immunoglobulin superfamily member 11 isoform h precursor
NM_001353325.2 NP_001340254.1 immunoglobulin superfamily member 11 isoform i
NM_001353326.2 NP_001340255.1 immunoglobulin superfamily member 11 isoform j
NM_152538.4 NP_689751.2 immunoglobulin superfamily member 11 isoform a precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ionotropic glutamate receptor binding IPI
IPI: 通过物理相互作用推断
26595655 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
26595655 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in homophilic cell adhesion via plasma membrane adhesion molecules IMP
IMP: 通过突变表型推断
15795899 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell-cell junction IDA
IDA: 通过直接分析推断
26595655 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

IGSF11 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (24 - 128)

Ig_3

Ig_3: Immunoglobulin domain (150 - 219)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 431 a.a.
蛋白主名 其他名称

immunoglobulin superfamily member 11

CXADR like 1

重组 IGSF11 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70854 IGSF11 Protein, Human (HEK293, Fc) Q5DX21-1 (L23-G245) ≥95%
HY-P76411 IGSF11 Protein, Human (HEK293, His) AAH34411.1 (E23-G240) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06647 IGSF11 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus IGSF11 VGNC VGNC:53583
Felis catus IGSF11 VGNC VGNC:62895
Mus musculus IGSF11 MGD MGI:2388477
Canis familiaris IGSF11 VGNC VGNC:53077
Macaca mulatta IGSF11 VGNC VGNC:73608
Rattus norvegicus IGSF11 RGD RGD:1308758
Others IGSF11 NCBI
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