CYP2D7 - cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene) Gene

中文名称：细胞色素 P450 家族 2 亚家族 D 成员 7 (基因/假基因)

种属: Homo sapiens

同用名: CYP2D; CYP2D6; CYP2D@; CYP2D7P; P450C2D; P450DB1; CYP2D7AP; CYP2D7P1; RNA40057

关于 CYP2D7

功能概要

该基因是细胞色素 P450 基因超家族的成员。细胞色素 P450 蛋白是单加氧酶，可催化许多涉及药物代谢和胆固醇、类固醇和其他脂质合成的反应。该基因是一个分离的假基因，其中一些个体可能具有编码功能性酶的等位基因，而其他个体具有编码预计无功能的蛋白质的等位基因。在这种情况下，功能等位基因被认为是罕见的。该位点是 22 号染色体上细胞色素 P450 基因簇的一部分。[RefSeq 提供，2017 年 1 月]

This gene is a member of the Cytochrome P450 gene superfamily. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of Cholesterol, Steroids and Other lipids. This gene is a segregating pseudogene, where some individuals may have an allele that encodes a functional Enzyme, while Other individuals have an allele encoding a protein that is predicted to be non-functional. In this case, the functional allele is thought to be rare. This locus is part of a cluster of Cytochrome P450 genes on chromosome 22. [provided by RefSeq, Jan 2017]