2. Gene
  3. Ifnb1 - interferon beta 1, fibroblast Gene

Ifnb1 - interferon beta 1, fibroblast Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ifb; IFNB; If1da1; IFN-beta

基因 ID: 15977 | 基因类型: protein coding

关于 Ifnb1

功能概要

Enables cytokine activity and type I interferon receptor binding activity. Involved in B cell proliferation; cellular response to virus; and type I interferon signaling pathway. Acts upstream of or within several processes, including cellular response to organic cyclic compound; defense response to Other organism; and negative regulation of osteoclast differentiation. Located in extracellular space. Is expressed in embryo and liver. Human ortholog(s) of this gene implicated in COVID-19. Orthologous to human IFNB1 (interferon beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Ifnb1 基因产物(1)

mRNA Protein Name
NM_010510.2 NP_034640.1 interferon beta precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cytokine activity IDA
IDA: 通过直接分析推断
15240719 MGI
enables type I interferon receptor binding IPI
IPI: 通过物理相互作用推断
23872679 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in B cell proliferation IMP
IMP: 通过突变表型推断
14597717 MGI
acts upstream of or within adaptive immune response IDA
IDA: 通过直接分析推断
17277142 MGI
acts upstream of or within cellular response to dexamethasone stimulus IDA
IDA: 通过直接分析推断
21606371 MGI
involved in cellular response to dsRNA IEP
IEP: 通过表达模式推断
18596219 MGI
involved in cellular response to virus IDA
IDA: 通过直接分析推断
24882218 MGI
acts upstream of or within defense response to bacterium IDA
IDA: 通过直接分析推断
15240719 MGI
acts upstream of or within defense response to virus IDA
IDA: 通过直接分析推断
17277142 MGI
involved in defense response to virus IDA
IDA: 通过直接分析推断
10708458 MGI
involved in defense response to virus IMP
IMP: 通过突变表型推断
27129230 MGI
acts upstream of or within humoral immune response IDA
IDA: 通过直接分析推断
17277142 MGI
involved in negative regulation of Lewy body formation IMP
IMP: 通过突变表型推断
26451483 MGI
acts upstream of or within negative regulation of osteoclast differentiation IDA
IDA: 通过直接分析推断
17442941 MGI
involved in neuron cellular homeostasis IMP
IMP: 通过突变表型推断
26451483 MGI
involved in positive regulation of autophagy IMP
IMP: 通过突变表型推断
26451483 MGI
involved in type I interferon-mediated signaling pathway IMP
IMP: 通过突变表型推断
27129230 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
17277142 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

interferon beta

interferon 1da1

重组 Ifnb1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73130 IFN-beta Protein, Mouse (HEK293) P01575 (I22-N182) ≥95%
HY-P73131 IFN-beta Protein, Mouse (HEK293, Fc) P01575 (I22-N182) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-138682 STING-IN-2 Inhibitor 99.71% 否
HY-RS06585 IFNB1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990036 Dazukibart Inhibitor 99.76% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ifnb1 NCBI NCBI:3456
Macaca mulatta Ifnb1 NCBI NCBI:711414
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