2. Gene
  3. Il18r1 - interleukin 18 receptor 1 Gene

Il18r1 - interleukin 18 receptor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Il1rrp; Il18ralpha

基因 ID: 16182 | 基因类型: protein coding

关于 Il18r1

功能概要

Enables interleukin-18 receptor activity. Involved in negative regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including interleukin-18-mediated signaling pathway; positive regulation of NIK/NF-kappaB signaling; and positive regulation of interferon-gamma production. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of interleukin-18 receptor complex. Is expressed in dorsal aorta; gonad; mesonephros; and thymus primordium. Human ortholog(s) of this gene implicated in asthma. Orthologous to human IL18R1 (interleukin 18 receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Il18r1 基因产物(3)

mRNA Protein Name
NM_001161842.1 NP_001155314.1 interleukin-18 receptor 1 isoform b precursor
NM_001161843.1 NP_001155315.1 interleukin-18 receptor 1 isoform b precursor
NM_008365.2 NP_032391.1 interleukin-18 receptor 1 isoform a precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables interleukin-18 receptor activity IMP
IMP: 通过突变表型推断
10227969 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
26099046 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within T-helper 1 cell differentiation IMP
IMP: 通过突变表型推断
10227969 MGI
acts upstream of or within interleukin-18-mediated signaling pathway IMP
IMP: 通过突变表型推断
10227969 MGI
acts upstream of or within natural killer cell activation IMP
IMP: 通过突变表型推断
10227969 MGI
involved in negative regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
26656097 MGI
involved in positive regulation of non-canonical NF-kappaB signal transduction IMP
IMP: 通过突变表型推断
10227969 MGI
acts upstream of or within positive regulation of type II interferon production IMP
IMP: 通过突变表型推断
10227969 MGI
acts upstream of type II interferon production IMP
IMP: 通过突变表型推断
10227969 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

interleukin-18 receptor 1

CD218 antigen-like family member A

IL-18R-1

IL-18R-alpha

IL-18R1

IL-18Ralpha

IL-1Rrp

IL1 receptor-related protein

IL1R-rp

interleukin 1 receptor related protein

interleukin-18 receptor alpha

重组 Il18r1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75845 IL-18R alpha Protein, Mouse (HEK293, Fc) Q61098 (K20-G326) ≥95%
HY-P75846 IL-18R alpha Protein, Mouse (HEK293, His-Fc) Q61098 (K20-G326) ≥95%
HY-P75847 IL-18R alpha Protein, Mouse (HEK293, His) Q61098/NP_032391.1 (K20-G326) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06710 IL18R1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Il18r1 NCBI NCBI:8809
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