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  2. Il6ra - interleukin 6 receptor, alpha Gene

Il6ra - interleukin 6 receptor, alpha Gene

种属: Mus musculus

同用名: Il6r; CD126; IL-6R; IL-6RA; IL-6R-alpha

基因 ID: 16194 | 基因类型: protein coding

关于 Il6ra

功能概要

Enables interleukin-6 binding activity and interleukin-6 receptor activity. Involved in T-helper 17 cell lineage commitment and interleukin-6-mediated signaling pathway. Located in cell surface. Part of interleukin-6 receptor complex. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; hemolymphoid system; and nervous system. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; hyper IgE syndrome; obesity; and stomach Cancer. Orthologous to human IL6R (interleukin 6 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Il6ra 基因产物(2)

mRNA Protein Name
NM_001310676.1 NP_001297605.1 interleukin-6 receptor subunit alpha isoform 2 precursor
NM_010559.3 NP_034689.2 interleukin-6 receptor subunit alpha isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables interleukin-6 receptor activity IDA
IDA: 通过直接分析推断
27893700 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in T-helper 17 cell lineage commitment IDA
IDA: 通过直接分析推断
27893700 MGI
acts upstream of or within interleukin-6-mediated signaling pathway IDA
IDA: 通过直接分析推断
1312474 MGI
involved in interleukin-6-mediated signaling pathway IDA
IDA: 通过直接分析推断
27893700 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of interleukin-6 receptor complex IDA
IDA: 通过直接分析推断
27893700 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

interleukin-6 receptor subunit alpha

IL-6 receptor alpha chain

IL-6 receptor subunit alpha

IL-6R 1

IL-6R subunit alpha

重组 Il6ra 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72538 IL-6R alpha Protein, Mouse (HEK293, His) P22272 (L20-P364) ≥95%