RASSF6 - Ras association domain family member 6 Gene

中文名称：Ras 关联域家族成员 6

种属: Homo sapiens

关于 RASSF6

功能概要

该基因编码 Ras 关联域家族 (RASSF) 的成员。这个家族的成员构成了一个高度保守的肿瘤抑制网络的核心，即 Salvador-Warts-Hippo (SWH) 通路。该基因编码的蛋白质是一种诱导细胞凋亡的 Ras 效应蛋白。含有该基因的基因组区域与病毒性细支气管炎的易感性有关。可变剪接导致多种转录本变体和蛋白质同种型。[RefSeq 提供，2012 年 7 月]

This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces Apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]