1. Gene
  2. Lgals9 - lectin, galactose binding, soluble 9 Gene

Lgals9 - lectin, galactose binding, soluble 9 Gene

种属: Mus musculus

同用名: gal-9; Lgals5; LGALS35; galectin-9

基因 ID: 16859 | 基因类型: protein coding

关于 Lgals9

功能概要

Enables several functions, including carbohydrate binding activity; galactoside binding activity; and protein serine/threonine kinase activator activity. Involved in several processes, including regulation of cytokine production; regulation of defense response; and regulation of leukocyte activation. Located in cytoplasm and nucleus. Is expressed in several structures, including cardiovascular system; hemolymphoid system; intestine; liver; and metanephros. Orthologous to several human genes including LGALS9 (Galectin 9). [provided by Alliance of Genome Resources, Apr 2022]

Lgals9 基因产物(2)

mRNA Protein Name
NM_001159301.1 NP_001152773.1 galectin-9 isoform 2
NM_010708.2 NP_034838.2 galectin-9 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables carbohydrate binding IDA
IDA: 通过直接分析推断
23242525 MGI
enables carbohydrate binding IMP
IMP: 通过突变表型推断
21670307 MGI
enables enzyme binding IPI
IPI: 通过物理相互作用推断
21670307 MGI
enables galactoside binding IMP
IMP: 通过突变表型推断
25065622 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
16286920 MGI
enables protein serine/threonine kinase activator activity IDA
IDA: 通过直接分析推断
25065622 MGI
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
25065622 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to virus IMP
IMP: 通过突变表型推断
23408620 MGI
involved in female pregnancy IDA
IDA: 通过直接分析推断
23242525 MGI
involved in maintenance of protein location IDA
IDA: 通过直接分析推断
21670307 MGI
involved in negative regulation of CD4-positive, alpha-beta T cell proliferation IMP
IMP: 通过突变表型推断
25065622 MGI
involved in negative regulation of gene expression IMP
IMP: 通过突变表型推断
23408620 MGI
involved in negative regulation of inflammatory response IMP
IMP: 通过突变表型推断
25065622 MGI
involved in negative regulation of natural killer cell activation IMP
IMP: 通过突变表型推断
23408620 MGI
involved in negative regulation of natural killer cell degranulation IMP
IMP: 通过突变表型推断
23408620 MGI
involved in negative regulation of type II interferon production IDA
IDA: 通过直接分析推断
23242525 MGI
involved in negative regulation of type II interferon production IMP
IMP: 通过突变表型推断
23408620 MGI
involved in positive regulation of SMAD protein signal transduction IMP
IMP: 通过突变表型推断
25065622 MGI
involved in positive regulation of T cell migration IDA
IDA: 通过直接分析推断
21670307 MGI
involved in positive regulation of chemokine production IMP
IMP: 通过突变表型推断
20937702 MGI
involved in positive regulation of cytokine production IMP
IMP: 通过突变表型推断
20937702 MGI
involved in positive regulation of defense response to bacterium IMP
IMP: 通过突变表型推断
20937702 MGI
involved in positive regulation of innate immune response IMP
IMP: 通过突变表型推断
20937702 MGI
involved in positive regulation of interleukin-1 production IMP
IMP: 通过突变表型推断
20937702 MGI
involved in positive regulation of interleukin-10 production IMP
IMP: 通过突变表型推断
25065622 MGI
involved in positive regulation of interleukin-6 production IMP
IMP: 通过突变表型推断
25158758 MGI
involved in positive regulation of macrophage activation IMP
IMP: 通过突变表型推断
20937702 MGI
involved in positive regulation of oxidoreductase activity IDA
IDA: 通过直接分析推断
21670307 MGI
involved in positive regulation of regulatory T cell differentiation IMP
IMP: 通过突变表型推断
25065622 MGI
involved in positive regulation of tumor necrosis factor production IMP
IMP: 通过突变表型推断
25158758 MGI
involved in receptor clustering IDA
IDA: 通过直接分析推断
25065622 MGI
NOT involved in regulation of T cell chemotaxis IDA
IDA: 通过直接分析推断
21670307 MGI
NOT involved in regulation of T cell differentiation in thymus IMP
IMP: 通过突变表型推断
25065622 MGI
NOT involved in regulation of T-helper 17 type immune response IMP
IMP: 通过突变表型推断
25065622 MGI
involved in regulation of natural killer cell differentiation IMP
IMP: 通过突变表型推断
23408620 MGI
involved in response to lipopolysaccharide IMP
IMP: 通过突变表型推断
25158758 MGI
involved in transforming growth factor beta receptor signaling pathway IMP
IMP: 通过突变表型推断
25065622 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
23242525 MGI
located in nucleus IDA
IDA: 通过直接分析推断
23242525 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

galectin-9

lectin, galactose binding, soluble 5

重组 Lgals9 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72637 Galectin-9/LGALS9 Protein, Mouse (GST) O08573-2 (M1-T322) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lgals9 NCBI NCBI:3965