2. Gene
  3. Alad - aminolevulinate, delta-, dehydratase Gene

Alad - aminolevulinate, delta-, dehydratase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Lv; ALADH

基因 ID: 17025 | 基因类型: protein coding

关于 Alad

功能概要

Enables identical protein binding activity and porphobilinogen synthase activity. Acts upstream of or within cellular response to interleukin-4 and heme biosynthetic process. Predicted to be located in extracellular space. Predicted to be active in cytosol. Is expressed in several structures, including liver; lung; metanephros; spleen; and yolk sac. Human ortholog(s) of this gene implicated in porphyria cutanea tarda and sickle cell anemia. Orthologous to human ALAD (aminolevulinate dehydratase). [provided by Alliance of Genome Resources, Apr 2022]

Alad 基因产物(2)

mRNA Protein Name
NM_001276446.1 NP_001263375.1 delta-aminolevulinic acid dehydratase
NM_008525.4 NP_032551.3 delta-aminolevulinic acid dehydratase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables porphobilinogen synthase activity IDA
IDA: 通过直接分析推断
4959158 MGI
enables porphobilinogen synthase activity IMP
IMP: 通过突变表型推断
5393940 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to interleukin-4 IDA
IDA: 通过直接分析推断
9798653 MGI
involved in heme A biosynthetic process IDA
IDA: 通过直接分析推断
14050799 MGI
involved in heme A biosynthetic process IMP
IMP: 通过突变表型推断
5393940 MGI
involved in heme B biosynthetic process IDA
IDA: 通过直接分析推断
14050799 MGI
involved in heme B biosynthetic process IMP
IMP: 通过突变表型推断
5393940 MGI
involved in heme O biosynthetic process IDA
IDA: 通过直接分析推断
14050799 MGI
involved in heme O biosynthetic process IMP
IMP: 通过突变表型推断
5393940 MGI
acts upstream of or within heme biosynthetic process IDA
IDA: 通过直接分析推断
4959158 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cytosol IDA
IDA: 通过直接分析推断
4981581 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

delta-aminolevulinic acid dehydratase

porphobilinogen synthase

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00553 ALAD Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Alad NCBI NCBI:210
Macaca fascicularis Alad NCBI NCBI:102130527
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