2. Gene
  3. Kirrel - kirre like nephrin family adhesion molecule 1 Gene

Kirrel - kirre like nephrin family adhesion molecule 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Neph1; Kirrel1; 6720469N11Rik

基因 ID: 170643 | 基因类型: protein coding

关于 Kirrel

功能概要

Predicted to enable cell adhesion molecule binding activity and Myosin binding activity. Acts upstream of or within several processes, including excretion; negative regulation of protein phosphorylation; and positive regulation of actin filament polymerization. Located in cell-cell junction; dendritic shaft; and plasma membrane. Is expressed in craniocervical region bone; glomerular tuft; lung; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in nephrotic syndrome type 23. Orthologous to human KIRREL1 (kirre like nephrin family adhesion molecule 1). [provided by Alliance of Genome Resources, Apr 2022]

Kirrel 基因产物(3)

mRNA Protein Name
NM_001170985.2 NP_001164456.1 kin of IRRE-like protein 1 isoform 1 precursor
NM_001377046.1 NP_001363975.1 kin of IRRE-like protein 1 isoform 2 precursor
NM_130867.4 NP_570937.2 kin of IRRE-like protein 1 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17923684 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell-cell adhesion IDA
IDA: 通过直接分析推断
21306299 MGI
acts upstream of or within cell-cell adhesion IGI
IGI: 通过遗传相互作用推断
21306299 MGI
acts upstream of or within negative regulation of protein phosphorylation IGI
IGI: 通过遗传相互作用推断
21306299 MGI
acts upstream of or within positive regulation of actin filament polymerization IGI
IGI: 通过遗传相互作用推断
17923684 MGI
acts upstream of or within renal protein absorption IMP
IMP: 通过突变表型推断
11416156 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell-cell junction IDA
IDA: 通过直接分析推断
21306299 MGI
located in dendritic shaft IDA
IDA: 通过直接分析推断
16874800 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
17923684 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

kin of IRRE-like protein 1

kin of IRRE like 1

kin of irregular chiasm-like protein 1

nephrin 1

nephrin-like protein 1

重组 Kirrel 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70866 Kirrel1/NEPH1 Protein, Mouse (HEK293, His) Q80W68-1 (L48-L525) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07312 KIRREL1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS07313 KIRREL2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS07314 KIRREL3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus Kirrel NCBI
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