2. Gene
  3. Kitl - kit ligand Gene

Kitl - kit ligand Gene

  • 基因
  • 蛋白
  • 直系同源

种属: Mus musculus

同用名: Gb; SF; Sl; Clo; Con; Mgf; SCF; SLF; blz; Kitlg; contrasted

基因 ID: 17311 | 基因类型: protein coding

关于 Kitl

功能概要

Enables cytokine activity and stem cell factor receptor binding activity. Acts upstream of or within several processes, including positive regulation of cell differentiation; positive regulation of cell population proliferation; and positive regulation of protein phosphorylation. Located in extracellular space and plasma membrane. Is integral component of membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 69 and familial progressive hyperpigmentation with or without hypopigmentation. Orthologous to human KITLG (KIT ligand). [provided by Alliance of Genome Resources, Apr 2022]

Kitl 基因产物(2)

mRNA Protein Name
NM_001347156.1 NP_001334085.1 kit ligand isoform 2 precursor
NM_013598.3 NP_038626.1 kit ligand isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cytokine activity IDA
IDA: 通过直接分析推断
12714518 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
1698557 MGI
enables stem cell factor receptor binding IDA
IDA: 通过直接分析推断
10872802 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of Ras protein signal transduction IDA
IDA: 通过直接分析推断
11435472 MGI
acts upstream of T cell proliferation IDA
IDA: 通过直接分析推断
15947484 MGI
acts upstream of apoptotic process IGI
IGI: 通过遗传相互作用推断
17107997 MGI
acts upstream of cell population proliferation IDA
IDA: 通过直接分析推断
11401406 MGI
acts upstream of cell population proliferation IGI
IGI: 通过遗传相互作用推断
7690439 MGI
acts upstream of or within ectopic germ cell programmed cell death IMP
IMP: 通过突变表型推断
17107997 MGI
acts upstream of or within extrinsic apoptotic signaling pathway in absence of ligand IDA
IDA: 通过直接分析推断
15039234 MGI
acts upstream of hematopoietic progenitor cell differentiation IGI
IGI: 通过遗传相互作用推断
1375116 MGI
acts upstream of mast cell apoptotic process IDA
IDA: 通过直接分析推断
12714518 MGI
acts upstream of mast cell migration IDA
IDA: 通过直接分析推断
24068671 MGI
acts upstream of mast cell proliferation IDA
IDA: 通过直接分析推断
11435472 MGI
acts upstream of mast cell proliferation IGI
IGI: 通过遗传相互作用推断
10620616 MGI
acts upstream of or within melanocyte migration IDA
IDA: 通过直接分析推断
11401406 MGI
acts upstream of myeloid leukocyte differentiation IGI
IGI: 通过遗传相互作用推断
1375116 MGI
acts upstream of or within negative regulation of apoptotic process IGI
IGI: 通过遗传相互作用推断
17107997 MGI
acts upstream of or within negative regulation of mast cell apoptotic process IDA
IDA: 通过直接分析推断
12714518 MGI
acts upstream of or within neural crest cell migration IDA
IDA: 通过直接分析推断
11401406 MGI
acts upstream of peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
10872802 MGI
acts upstream of or within positive regulation of MAP kinase activity IGI
IGI: 通过遗传相互作用推断
10620616 MGI
acts upstream of or within positive regulation of Ras protein signal transduction IDA
IDA: 通过直接分析推断
11435472 MGI
acts upstream of or within positive regulation of T cell proliferation IDA
IDA: 通过直接分析推断
15947484 MGI
acts upstream of or within positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
11401406 MGI
acts upstream of or within positive regulation of cell population proliferation IGI
IGI: 通过遗传相互作用推断
7690439 MGI
acts upstream of or within positive regulation of hematopoietic progenitor cell differentiation IGI
IGI: 通过遗传相互作用推断
1375116 MGI
acts upstream of or within positive regulation of hematopoietic stem cell proliferation IDA
IDA: 通过直接分析推断
21540074 MGI
acts upstream of or within positive regulation of leukocyte migration IDA
IDA: 通过直接分析推断
24068671 MGI
acts upstream of or within positive regulation of mast cell proliferation IDA
IDA: 通过直接分析推断
11435472 MGI
acts upstream of or within positive regulation of mast cell proliferation IGI
IGI: 通过遗传相互作用推断
10620616 MGI
acts upstream of or within positive regulation of melanocyte differentiation IDA
IDA: 通过直接分析推断
16427619 MGI
acts upstream of or within positive regulation of myeloid leukocyte differentiation IGI
IGI: 通过遗传相互作用推断
1375116 MGI
acts upstream of or within positive regulation of peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
10872802 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
7690439 MGI
located in membrane IDA
IDA: 通过直接分析推断
12140361 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
14525951 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

kit ligand

C-kit ligand

Steel factor

cloud gray

grizzle-belly

hematopoietic growth factor KL

mast cell growth factor

stem cell factor

重组 Kitl 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7064 SCF Protein, Mouse (P.pastoris) P20826 (K26-A189) ≥95%
HY-P70528 SCF Protein, Mouse P20826 (K26-A189) ≥95%
HY-P70555 SCF Protein, Mouse (HEK293, His) P20826 (K26-A189) ≥95%
HY-P73662 SCF Protein, Mouse (sf9, His) P20826 (M1-A189) ≥95%
HY-P77529 SCF Protein, Mouse (Biotinylated, sf9, His) P20826 (M1-A189) ≥95%

直系同源

种属 基因名 来源 基因 ID
Canis familiaris Kitl NCBI
Rattus norvegicus Kitl NCBI
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