2. Gene
  3. Ncam1 - neural cell adhesion molecule 1 Gene

Ncam1 - neural cell adhesion molecule 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CD56; Ncam; E-NCAM; NCAM-1

基因 ID: 17967 | 基因类型: protein coding

关于 Ncam1

功能概要

Predicted to enable LRR domain binding activity and Phosphatase binding activity. Involved in commissural neuron axon guidance and regulation of semaphorin-plexin signaling pathway. Acts upstream of or within several processes, including homotypic cell-cell adhesion; positive regulation of calcium-mediated signaling; and regulation of exocyst assembly. Located in several cellular components, including external side of plasma membrane; growth cone; and neuronal cell body. Is expressed in several structures, including embryo mesenchyme; nervous system; sensory organ; skin; and urinary system. Human ortholog(s) of this gene implicated in bipolar disorder; middle cerebral artery infarction; and pancreatic Cancer. Orthologous to human NCAM1 (neural cell adhesion molecule 1). [provided by Alliance of Genome Resources, Apr 2022]

Ncam1 基因产物(5)

mRNA Protein Name
NM_001081445.2 NP_001074914.1 neural cell adhesion molecule 1 isoform 1 precursor
NM_001113204.2 NP_001106675.1 neural cell adhesion molecule 1 isoform 3 precursor
NM_001311065.2 NP_001297994.1 neural cell adhesion molecule 1 isoform 4 precursor
NM_001404722.1 NP_001391651.1 neural cell adhesion molecule 1 isoform 5 precursor
NM_010875.4 NP_035005.2 neural cell adhesion molecule 1 isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10772929 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of calcium-mediated signaling IDA
IDA: 通过直接分析推断
7613634 MGI
acts upstream of or within cell surface receptor signaling pathway IDA
IDA: 通过直接分析推断
7613634 MGI
involved in commissural neuron axon guidance IGI
IGI: 通过遗传相互作用推断
22998873 MGI
involved in epithelial to mesenchymal transition IDA
IDA: 通过直接分析推断
28098160 MGI
acts upstream of or within homotypic cell-cell adhesion IMP
IMP: 通过突变表型推断
7613634 MGI
acts upstream of or within neuron projection development IGI
IGI: 通过遗传相互作用推断
21389209 MGI
acts upstream of or within positive regulation of calcium-mediated signaling IDA
IDA: 通过直接分析推断
7613634 MGI
acts upstream of or within regulation of exocyst assembly IMP
IMP: 通过突变表型推断
21389209 MGI
involved in regulation of semaphorin-plexin signaling pathway IGI
IGI: 通过遗传相互作用推断
22998873 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
15065125 MGI
located in cell-cell junction IDA
IDA: 通过直接分析推断
23284756 MGI
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
7613634 MGI
located in growth cone IDA
IDA: 通过直接分析推断
21389209 MGI
located in neuronal cell body IDA
IDA: 通过直接分析推断
15065125 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neural cell adhesion molecule 1

N-CAM-1

重组 Ncam1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P78764 NCAM-1/CD56 Protein, Mouse (HEK293, His) P13595 (L20-T711) ≥95%

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99372 Lorvotuzumab 99.77% Phase 2
Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09063 NCAM1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ncam1 NCBI NCBI:4684
Macaca fascicularis Ncam1 NCBI NCBI:102144192
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