1. Gene
  2. DPT - dermatopontin Gene

DPT - dermatopontin Gene

中文名称:皮桥蛋白

种属: Homo sapiens

同用名: TRAMP

基因 ID: 1805 | 基因类型: protein coding

关于 DPT

Cytogenetic location: 1q24.2 Genomic coordinates (GRCh38): 1:168,695,468-168,729,206 (from NCBI)

This gene has 1 transcript (splice variant) and 195 orthologues. Broad expression in fat (RPKM 269.7), heart (RPKM 73.0) and 14 other tissues.

功能概要

皮桥蛋白是一种细胞外基质蛋白,可能在细胞-基质相互作用和基质组装中发挥作用。该蛋白质存在于各种组织中,其许多酪氨酸残基被硫酸化。假定皮桥蛋白通过与核心蛋白聚糖的相互作用来改变 TGF-β 的行为。[RefSeq 提供,2008 年 7 月]

Dermatopontin is an extracellular matrix protein with possible functions in cell-matrix interactions and matrix assembly. The protein is found in various tissues and many of its tyrosine residues are sulphated. Dermatopontin is postulated to modify the behavior of TGF-beta through interaction with decorin. [provided by RefSeq, Jul 2008]

DPT 基因产物(1)

mRNA Protein Name
NM_001937.5 NP_001928.2 dermatopontin precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
30082873 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

DPT 蛋白结构

DERM

DERM: Dermatopontin (42 - 191)

  • 0
  • 100
  • 201 a.a.
蛋白主名 其他名称

dermatopontin

tyrosine-rich acidic matrix protein

重组 DPT 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72667 Dermatopontin/DPT Protein, Human (HEK293, Fc, His) Q07507 (Q19-V201) ≥95%

关联疾病

疾病名称 别名
Leiomyoma

Leiomyomatous Neoplasm

Leiomyomatous Tumor

Leiomyomas

Fibroid Tumor

Uterine Fibroids

Febrile Seizures, Familial, 4

FEB4

Convulsions, Familial Febrile, 4

Familial Febrile Seizures 4

Familial Febrile Convulsions 4

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris DPT VGNC VGNC:40080
Macaca mulatta DPT VGNC VGNC:71981
Rattus norvegicus DPT RGD RGD:1307176
Bos taurus DPT VGNC VGNC:28191
Felis catus DPT VGNC VGNC:61611
Mus musculus DPT MGD MGI:1928392
Others DPT NCBI