1. Gene
  2. Nxn - nucleoredoxin Gene

Nxn - nucleoredoxin Gene

种属: Mus musculus

同用名: l11Jus13

基因 ID: 18230 | 基因类型: protein coding

关于 Nxn

功能概要

Enables thioredoxin-disulfide reductase activity. Involved in circulatory system development; negative regulation of Wnt signaling pathway; and negative regulation of protein ubiquitination. Acts upstream of or within in utero embryonic development. Located in nucleus. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; musculoskeletal system; and nervous system. Human ortholog(s) of this gene implicated in Robinow syndrome. Orthologous to human NXN (nucleoredoxin). [provided by Alliance of Genome Resources, Apr 2022]

Nxn 基因产物(1)

mRNA Protein Name
NM_008750.5 NP_032776.1 nucleoredoxin
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16764867 MGI
enables thioredoxin-disulfide reductase (NADPH) activity IDA
IDA: 通过直接分析推断
9119370 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in circulatory system development IMP
IMP: 通过突变表型推断
20970343 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
27996060 MGI
involved in negative regulation of Wnt signaling pathway IMP
IMP: 通过突变表型推断
20970343 MGI
involved in negative regulation of protein ubiquitination IMP
IMP: 通过突变表型推断
20970343 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
9119370 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

nucleoredoxin

protein Red-1

Nxn 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Nxn P97346 SEC63 Homo sapiens Q9UGP8
Pull Down
21251912
种属间
Nxn P97346 SEC63 Homo sapiens Q9UGP8
Peptide Array
21251912
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nxn NCBI NCBI:64359